CyTOF

描述(申请人提供)：这份建议书要求600,000美元购买DVS Sciences，Inc.制造的带有自动96孔板阅读器和相关控制计算机的CyTOF ICP-TOF-MS C5型质量细胞仪。CyTOF是一种新型的细胞仪，它使用金属离子标记的试剂来检测不同的细胞成分。实用的流式细胞仪技术只允许10-12次同时测量，而CyTOF允许最多100次。希望使用这项技术的研究人员看到了个性化医学发展的巨大潜力，因为与传统的流式细胞术相比，使用CyTOF可以更完整地表征疾病状态和对各种治疗的反应。CyTOF将安装在斯坦福大学共享的FACS设施中，这是医学院的一个服务中心，为斯坦福大学和地区学术生物技术研究社区提供流式细胞仪仪器和技术专业知识。

DESCRIPTION (provided by applicant): This proposal requests $600,000 to purchase a CyTOF ICP-TOF-MS Model C5 mass cytometer with an automated 96 well plate reader and associated control computer made by DVS Sciences, Inc. The CyTOF is a new type of cytometer, which uses reagents labeled with metal ions instead of fluorescent dyes to detect different cellular constituents. Whereas practical flow cytometry techniques allow for only 10-12 simultaneous measurements, the CyTOF allows up to 100. The Investigators desiring to use this technology see great potential for advancement in personalized medicine as a more complete characterization of disease states and responses to various treatments is possible with the CyTOF compared to conventional flow cytometry. The CyTOF will be installed in the Stanford Shared FACS Facility, a Service Center in the School of Medicine that provides flow cytometry instruments and technical expertise to the Stanford and regional academic biotechnology research communities.