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联系PD/PI:克劳斯,黛安·S 项目摘要/摘要 耶鲁大学合作血液学专业核心中心(YCHSCC) 耶鲁大学合作血液学专科核心中心的宗旨是促进和加强 血液学研究,为研究人员提供通过Performance和 以教学为基础的方法。我们唯一的关注点是将新兴技术应用于正常和 在一个创新技术进步共享和积极的环境中扰乱了造血 用于促进血液学研究。青年会的更大目标是在以下方面发挥关键作用 其他NIDDK合作社提供的血液病相关研究支持的综合计划 血液学专业核心中心通过提供机会产生更多的互动和 与耶鲁大学和其他机构的血液学研究人员合作,以及促进 早期职业科学家的血液学研究。在青年管委会,四个新兴技术研究核心,一个 细胞准备和分析核心、成像核心、表达和基因组学核心和动物 建模核心为血液学研究人员提供最先进的技术并提供帮助。 每个新兴技术核心都有详细的教育和培训计划。这些核心也 评估和优化潜在的血液学应用的新技术和新兴技术。一项计划 对于内部和外部血液学调查人员来说,核心访问已经到位,这是一项促进访问的计划 由早期调查人员进行调查。核心的基础设施,以及基于费用的成本回收系统 在预算中立的情况下运作,对调查人员来说将是经济上的优势。一个丰富的计划 为血液学研究人员提供增进科学知识的机会 在几个论坛上交流信息,包括互动技术分享研讨会、正在进行的研究 演讲和实习生交流计划。一项试点和可行性计划促进了血液学研究 通过支持早期职业研究人员的工作,建立了血液学新手,并建立了 血液学研究人员追求新的研究目标。管理核心可促进 青年管委会,包括履行与行政、财务和人事有关的职能。教育和 血液学研究人员的培训是青年会不可或缺的职能。充分活跃,充分利用富人 耶鲁大学的环境,一个积极参与、合作的血液学研究基地,以及新兴血液学的专业知识 技术,基督教青年会将为血液学界提供重要的机会,推动在 研究。最终目标是改善血液病的诊断、治疗和预防。 项目摘要/摘要第72页
英文摘要
Contact PD/PI: Krause, Diane S Project Summary/Abstract Yale Cooperative Hematology Specialized Core Center (YCHSCC) The purpose of the Yale Cooperative Hematology Specialized Core Center is to facilitate and enhance hematology research by providing investigators access to state-of-the-art technologies via both performance and teaching-based approaches. Our unique focus is the application of emerging technologies to normal and perturbed hematopoiesis in an environment in which innovative technical advances are shared and positively leveraged for the advancement of hematologic research. The larger goal of the YCHSCC is to play a key role in the integrated program of hematologic diseases-related research support provided by other NIDDK Cooperative Hematology Specialized Core Centers by providing opportunities to engender increased interactions and collaborations with hematology investigators within Yale and at other institutions as well as to promote hematology research in early career scientists. In the YCHSCC, four Emerging Technology research cores, a Cell Preparation and Analysis Core, an Imaging Core, an Expression and Genomics Core, and an Animal Modeling Core provide hematology investigators access to and assistance with state-of-the art technologies. Detailed education and training programs are in place for each Emerging Technology Core. These cores also evaluate and optimize new and emerging technologies for potential hematology-based applications. A program for Core access is in place for both internal and external hematology investigators, as is a plan to facilitate access by early stage investigators. Infrastructure for the cores, with fee-based cost recovery systems in place for operation at budget neutrality, will be financially advantageous for investigators. An Enrichment Program provides opportunities for hematology investigators to enhance their scientific knowledge by facilitating the exchange of information in several forums including interactive technique sharing symposia, research in progress presentations, and trainee exchange programs. A Pilot and Feasibility Program promotes hematology research by supporting work of early career investigators, established investigators new to hematology, and established hematology investigators pursuing novel research objectives. An Administrative Core facilitates operations of the YCHSCC, including performing administrative, financial, and personnel-related functions. Education and training of hematology investigators are integral functions of the YCHSCC. Fully active, leveraging the rich environment of Yale University, an engaged, collaborative hematology research base, and expertise in emerging technologies, the YCHSCC will provide the hematology community significant opportunities to drive advances in research. The ultimate goal is to improve diagnosis, treatment, and prevention of hematologic disease. Project Summary/Abstract Page 72
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Novel Mechanisms of Congenital Dyserythropoietic Anemia
  • 批准号:
    10454333
  • 项目类别:
  • 资助金额:
    $41.84万
  • 财政年份:
    2020
  • 负责人:
    PATRICK G GALLAGHER
  • 依托单位:
Novel Mechanisms of Congenital Dyserythropoietic Anemia
  • 批准号:
    9887377
  • 项目类别:
  • 资助金额:
    $41.84万
  • 财政年份:
    2020
  • 负责人:
    PATRICK G GALLAGHER
  • 依托单位:
Novel Mechanisms of Congenital Dyserythropoietic Anemia
  • 批准号:
    10192709
  • 项目类别:
  • 资助金额:
    $41.84万
  • 财政年份:
    2020
  • 负责人:
    PATRICK G GALLAGHER
  • 依托单位:
Nonenzymatic Gene Editing in Treatment of Heredity Spherocytosis
  • 批准号:
    10305603
  • 项目类别:
  • 资助金额:
    $62.02万
  • 财政年份:
    2019
  • 负责人:
    PATRICK G GALLAGHER
  • 依托单位:
海外基金