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中文摘要
翻译
在这一年里,弗格森博士实现了几个目标。首先,她在早产儿病例对照研究中收集了尿中微量金属和非靶向代谢组学数据。这是儿童健康接触评估资源下的一个试点项目。这个项目的几份手稿正在准备中,总结了尿液中微量金属与早产和先兆子痫之间的关系以及混合物的发现。其次,Ferguson博士与杜克分子生理学研究所(Duke Molecular Physiology Institute)的合作者合作,在一项试点病例对照研究中,研究了非靶向尿液代谢组学特征与生长限制之间的关系。这项研究的结果目前正在准备发表。最后,她发起了一个试点项目,创建一个新的病例对照研究,旨在调查产前环境暴露与怀孕期间胎儿生长障碍之间的关系。
英文摘要
Over the course of this year, Dr. Ferguson met several goals. First, she collected data on urinary trace metals and non-targeted metabolomic profiles within the case-control study of preterm birth. This was a pilot project under the Childrens Health Exposure Assessment Resource. Several manuscripts from this project are in preparation, summarizing findings on the relationships between urinary trace metals individually as well as in mixtures in relation to preterm birth as well as preeclampsia. Second, Dr. Ferguson worked with collaborators at the Duke Molecular Physiology Institute to examine the relationship between non-targeted urinary metabolomic profiles in relation to growth restriction in a pilot case-control study. Findings from this study are currently in preparation for publication. Finally, she initiated a pilot project for the creation of a new case-control study designed to investigate the relationship between prenatal environmental exposures and disorders of fetal growth in pregnancy.
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LIFECODES pregnancy cohort
Environmental phthalate exposure in the Human Placenta Project cohort
The Generation R cohort study as an NIEHS resource
Phthalate and stressful life event exposures and pregnancy outcomes: The role of oxidative stress
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