Oxidative stress as a mediator of environmental exposure impacts on fertility endpoints
Oxidative stress as a mediator of environmental exposure impacts on fertility endpoints
批准号:
9352172
负责人:
Kelly Ferguson
金额:
$6.94万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
AddressAntralAreaBiological MarkersBostonCalendarChemical ExposureChemicalsClinicalComet AssayCouplesDNADNA DamageDataDinoprostEconomic BurdenEnvironmentEnvironmental ExposureEnvironmental HealthEnvironmental PollutionEpidemiologyExposure toF2-IsoprostanesFemaleFertilityFertilization in VitroGeneral HospitalsGerm CellsGoalsInfertilityLaboratoriesLinkLipid PeroxidationLiteratureLive BirthMassachusettsMeasuresMediationMediator of activation proteinMorphologyOocytesOutcomeOutcome MeasureOxidative StressPopulationPregnancyPregnancy OutcomePregnancy lossPreventionPsychological StressPublishingRecruitment ActivityReproductive HealthResearchSeminal fluidSperm Count ProcedureTailTimeWomancell motilitycohortimplantationinfertility treatmentinterestmalemenphthalatesprimary outcomeprospectivereproductivesample collectionsperm cellsperm morphologysuccesstoxicanturinary
中文摘要
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英文摘要
This project extends Dr. Fergusons research into oxidative stress as a unifying mechanism connecting environmental contaminant exposure to adverse reproductive and pregnancy outcomes. The concept for this project was presented to the Epidemiology Branch in August of 2016 and received approval. We have additionally made progress toward selecting a laboratory for analysis of oxidative stress measures, and toward identifying subjects and specific time points of sample collection that we will utilize in the present study. Over the next calendar year we anticipate completion of urinary oxidative stress biomarker analysis and publishing the primary findings from this study.
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LIFECODES pregnancy cohort
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批准号:10924978
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项目类别:
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资助金额:$105.57万
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财政年份:--
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负责人:Kelly Ferguson
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依托单位:
Environmental phthalate exposure in the Human Placenta Project cohort
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批准号:10924986
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项目类别:
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资助金额:$82.31万
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财政年份:--
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负责人:Kelly Ferguson
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依托单位:
The Generation R cohort study as an NIEHS resource
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批准号:10924956
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项目类别:
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资助金额:$8.95万
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财政年份:--
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负责人:Kelly Ferguson
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依托单位:
Phthalate and stressful life event exposures and pregnancy outcomes: The role of oxidative stress
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批准号:9550214
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项目类别:
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资助金额:$8.43万
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财政年份:--
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负责人:Kelly Ferguson
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依托单位:
LIFECODES pregnancy cohort
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批准号:9550228
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项目类别:
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资助金额:$16.85万
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财政年份:--
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负责人:Kelly Ferguson
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依托单位:
The Generation R cohort study as an NIEHS resource
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批准号:10008726
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项目类别:
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资助金额:$7.23万
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财政年份:--
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负责人:Kelly Ferguson
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依托单位:
Phthalate and stressful life event exposures and pregnancy outcomes: The role of oxidative stress
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批准号:10008732
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项目类别:
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资助金额:$59.67万
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财政年份:--
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负责人:Kelly Ferguson
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依托单位:
The Generation R cohort study as an NIEHS resource
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批准号:10249858
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项目类别:
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资助金额:$0.79万
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财政年份:--
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负责人:Kelly Ferguson
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依托单位:
LIFECODES pregnancy cohort
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批准号:9785218
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项目类别:
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资助金额:$47.04万
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财政年份:--
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负责人:Kelly Ferguson
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依托单位:
LIFECODES pregnancy cohort
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批准号:10248903
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项目类别:
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资助金额:$73.52万
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财政年份:--
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负责人:Kelly Ferguson
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依托单位:
Oxidative stress as a mediator of environmental exposure impacts on fertility endpoints
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批准号:10248902
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项目类别:
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资助金额:$17.88万
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财政年份:--
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负责人:Kelly Ferguson
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依托单位:
Environmental phthalate exposure in the Human Placenta Project cohort
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批准号:10248909
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项目类别:
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资助金额:$11.92万
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财政年份:--
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负责人:Kelly Ferguson
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依托单位:
Phthalate and stressful life event exposures and pregnancy outcomes: The role of oxidative stress
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批准号:9352171
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项目类别:
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资助金额:$6.94万
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财政年份:--
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负责人:Kelly Ferguson
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依托单位:
LIFECODES pregnancy cohort
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批准号:10008734
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项目类别:
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资助金额:$51.72万
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财政年份:--
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负责人:Kelly Ferguson
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依托单位:
Phthalate and stressful life event exposures and pregnancy outcomes: The role of oxidative stress
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批准号:10248901
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项目类别:
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资助金额:$15.5万
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财政年份:--
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负责人:Kelly Ferguson
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依托单位:
Oxidative stress as a mediator of environmental exposure impacts on fertility endpoints
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批准号:10008733
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项目类别:
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资助金额:$10.85万
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财政年份:--
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负责人:Kelly Ferguson
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依托单位:
海外基金