North Carolina Diabetes Research Center

项目摘要/摘要-基因组学和蛋白质组学核心 作为北卡罗来纳州糖尿病研究中心(NCDRC)的一部分，基因组和蛋白质组学核心(GPC) 将利用维克森林在基因组学和质谱学方面的最先进资源和专业知识 精密医学中心为高通量仪器和分析提供独特的途径 向NCDRC教职员工和附属成员提供专业知识，以支持正在进行的和未来的研究计划。GPC 建立在几名调查人员广泛的长期专业知识和经验的基础上，这些调查人员支持 基因组学、表观基因组学、蛋白质组学和生物信息学方面其他大规模研究工作的核心组成部分 和统计数据，以及谁都是维克森林大学健康精准医学中心的成员 科学。GPC还将协调现有基因组学、表观基因组学和蛋白质组学资源的使用 在伙伴机构(北卡罗来纳大学、北卡罗来纳大学和杜克大学)，并与 代谢组学核心，提供全套组学分析。NCDRC GPC将提供分析服务， 但同样重要的是，GPC将提供知识和工具，以整合数据以更好地理解 互动系统在疾病过程中发挥作用。

PROJECT SUMMARY/ABSTRACT – GENOMICS AND PROTEOMICS CORE As part of the North Carolina Diabetes Research Center (NCDRC), the Genomics and Proteomics Core (GPC) will utilize state-of-the-art resources and expertise in genomics and mass spectrometry at the Wake Forest Center for Precision Medicine to provide unique access to high-throughput instrumentation and analytical expertise to NCDRC faculty and affiliate members in support of ongoing and future research programs. The GPC builds on the extensive long-standing expertise and experience of several investigators who have supported Core components for other large-scale research efforts in genomics, epigenomics, proteomics and bioinformatics and statistics, and who are all part of the Center for Precision Medicine at Wake Forest University Health Sciences. The GPC will also coordinate the use of existing genomics, epigenomics, and proteomics resources at the partner institutions (UNC, NC A&T, and Duke University), and coordinate work and data analysis with the Metabolomics Core to provide the entire suite of omics analyses. The NCDRC GPC will offer analytic services, but equally importantly, the GPC will provide the knowledge and tools to integrate the data to better understand the interactive systems at play in disease processes.