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中文摘要
翻译
新英格兰地区卓越中心将利用发展项目计划促进 创新的,前沿的研究领域,可能产生的发现,将转化为创造 新的疫苗、治疗剂和/或诊断剂,以对抗NIAID的优先病原体和新出现的病原体。 传染病发展项目的资源将投资于研究项目, 最大的潜力发展到完整的NERCE研究计划或项目,将有竞争力的 传统的NIH资助。鉴于支助期限相对较短(一年或两年), 由于投资较小,开发项目的风险更大,所需的初步数据比 传统的“RO 1”类赠款。发展项目资金也将用于帮助建立新的 英格兰的研究人员将项目发展到可以利用NERCE核心的阶段 设施该基金将用于吸引不在生物防御领域工作的调查人员, 开始重点病原体的研究计划,并吸引机构和公司的调查人员 没有参加NERCE的人。最后,发展项目计划将用于鼓励 研究人员之间的合作,特别是基础和临床研究实验室之间的合作, 传统的微生物实验室和其他基础科学学科的研究人员(例如, 免疫学家、细胞生物学家、化学生物学家、生物信息学家)。为了创造最肥沃的 环境的发现,发展资金将用于对项目进行战略投资, 高风险但潜在高回报优先于传统小额赠款, 传统的NIH资助。
英文摘要
The New England Regional Center of Excellence will use the Developmental Projects program to promote innovative, cutting edge research in areas that may yield discoveries that would translate into the creation of new vaccines, therapeutics and/or diagnostics to combat NIAID priority pathogens and agents of emerging infectious disease. The Developmental Projects resources will be invested in research projects with the greatest potential to grow to full NERCE research programs or to projects that would be competitive for traditional NIH funding. Given the relatively short duration of support (one or two years) and the relatively small investment, the Developmental Projects will be more risky and require less preliminary data than conventional "RO1"-like grants. Developmental Project funds will also be used to help established New England investigators develop projects to the stage where they can take advantage of the NERCE core facilities. The fund will be used to attract investigators who are not working in the area of biodefense to begin research programs on priority pathogens and to attract investigators from institutions and companies that are not participating in NERCE. Finally, the Developmental Projects program will be used to encourage collaborations among investigators, particularly between basic and clinical research laboratories and between traditional microbiology laboratories and investigators in other basic science disciplines (e.g. immunologists, cell biologists, chemical biologists, bioinformaticists). In order to create the most fertile environment for discovery, developmental funds will be used to make strategic investments in projects of high risk but potentially high return preferentially over conventional small grants that are more likely to attract traditional NIH funding.
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Elucidating the Structural Requirements for Next-Gen Glycoconjugate Vaccines
  • 批准号:
    10321266
  • 项目类别:
  • 资助金额:
    $60.46万
  • 财政年份:
    2020
  • 负责人:
    Dennis L. Kasper
  • 依托单位:
Elucidating the Structural Requirements for Next-Gen Glycoconjugate Vaccines
  • 批准号:
    10533764
  • 项目类别:
  • 资助金额:
    $61.31万
  • 财政年份:
    2020
  • 负责人:
    Dennis L. Kasper
  • 依托单位:
Elucidating the Structural Requirements for Next-Gen Glycoconjugate Vaccines
  • 批准号:
    10084269
  • 项目类别:
  • 资助金额:
    $60.46万
  • 财政年份:
    2020
  • 负责人:
    Dennis L. Kasper
  • 依托单位:
Innovative Platforms for Antimicrobial Therapy and Vaccine Development
  • 批准号:
    8791872
  • 项目类别:
  • 资助金额:
    $493.25万
  • 财政年份:
    2014
  • 负责人:
    Dennis L. Kasper
  • 依托单位:
海外基金