Dermatoscopy in the Management of Xeroderma Pigmentosum

在与Kenneth Kraemer博士和John DiGiovanna博士的合作下，我们已经获得了几名色素性干皮病患者皮肤镜活检的色素性皮损的数字图像。这些患者已经在Kraemer博士的专注于色素性干皮病的临床方案的主持下在NIH临床中心就诊。目前，已从这些患者那里获得信息的20多个皮损正在使用标准皮肤镜标准进行分析，以寻找可能允许其临床分类为恶性或良性的特征。此外，有时还会对着色性干皮病患者的家庭成员进行皮肤镜检查，对选定的色素病变进行评估。该技术还被用于评估数量有限的毛发硫代营养不良患者。

In collaboration with Drs. Kenneth Kraemer and John Digiovanna, we have obtained digital dermatoscopic images of biopsied pigmented skin lesions on several patients with xeroderma pigmentosum. These patients have been seen at the NIH Clinical Center under the auspices of Dr. Kraemer's clinical protocol focused upon xeroderma pigmentosum. Currently the greater than twenty lesions whose information has been obtained from these patients are being analyzed, using standard dermatoscopic criteria, for features that may permit whether they can be classified clinically as malignant or benign. In addition, dermatoscopic evaluation of selected pigmented lesions on family members of those affected with xeroderma pigmentosum is sometimes performed. The technique has also been used to evaluate a limited number of patients with trichothiodystrophy.