Translational Core for Therapeutic and Diagnostic Development

项目摘要：治疗和诊断的翻译核心 发展 新提出的治疗和诊断开发翻译核心将满足以下需求： 越来越多的研究人员从事转化研究，以推进新的治疗和诊断 治疗眼科疾病的工具。该核心为科学家和临床医生提供资源， 观察到的实验室，在实验室调查这些发现，并采取新的理解回到 诊所，反之亦然。目标是为以下方面提供设施、专业知识和服务：1）临床 生物采样和表型分析（诊所到实验室），2）首次人体和机制研究（实验室到诊所），3） 生物统计和研究数据分析方面的咨询和援助，以及4）尖端和安全的 计算设施、先进软件、专门知识和研究方案制定方面的援助。的 提出的目标旨在提供专门的支持服务，以加快治疗和诊断 发展

PROJECT SUMMARY: TRANSLATIONAL CORE FOR THERAPEUTIC AND DIAGNOSTIC DEVELOPMENT The newly proposed Translational Core for Therapeutic and Diagnostic Development will fulfill the needs of a growing number of investigators engaged in translational research to advance new therapeutic and diagnostic tools for ophthalmic diseases. This Core provides resources for scientists and clinicians to bring clinical observations to the laboratory, investigate these findings in the laboratory and take new understanding back to the clinic or vice versa. The goals will be to provide facilities, expertise, and services for: 1) clinical biosampling and phenotyping (Clinic to Lab), 2) first-in-human and mechanistic studies (Lab to Clinic), 3) consultation and assistance in biostatistical and analyses of research data, and 4) cutting-edge and secured computing facilities, advanced software, expertise and assistance in research protocol development. The proposed goals are meant to provide dedicated support services to accelerate therapeutic and diagnostic development.