1/2 Southeast Partnership for Improving Research &Training in Cancer Health Disparities

摘要-行政核心 改善癌症健康差异研究和培训的东南伙伴关系（SPIRIT-CHD） 路易斯安那州州立大学健康科学中心（LSUHSC），一个服务不足的机构 人口和代表性不足的学生（IUPS），以及NCI指定的莫菲特癌症中心（MCC）， 关于癌症健康差异的生物学机制的先进转化研究，重点是 生物医学研究和精准医学教育。行政核心（AC）提供 使SPIRIT-CHD发挥作用所需的必要中央监督、协调、支持和后勤 有效地，与持续的沟通和改进是关键的责任。为此，AC 具有以下目标：a）监督规划活动; B）协调和监督试点研究 项目和癌症研究教育计划; c）促进合作者之间的富有成效的互动， 早期研究员（ESI）和学生; d）监测进展并进行组件评估 e）定期审查和修订短期和长期计划; f）确保最高的 所有项目和计划组成部分和活动的科学完整性标准，以及g）激励新的 与健康差距有关的研究合作;以及h）确保方案和核心之间的整合。 AC由一个多学科的既定调查小组领导，由内部顾问指导， 委员会由社区学术成员组成，并得到双方领导层的大力支持 机构职能体系它协同链接并建立在我们与其他PACHE、CURE和社区的经验之上 网络伙伴关系计划：将实施一系列规划和优先事项设定步骤， 定期和持续的互动，面对面的务虚会和其他沟通渠道，以促进：1）进行 一个试点研究计划开始于一个项目，该项目以乳腺癌基因组学为中心， 来自混合遗传祖先（非洲人、美洲原住民、欧洲人）的拉丁美洲患者的生物标本;以及2） 实施三管齐下的联合癌症研究教育计划，提供本科生和 医学生与暑期研究经验的手，提供课程和重点培训， 学生对生物银行，精准医学和癌症健康的差距，并扩大现有的 外联 教育我们各自的种族/少数民族社区。 重要的是，AC确保指导 并提供必要的反馈，以实现伙伴关系目标和SPIRIT-CHD的整合 件.总的来说，咨询委员会促进了协调和沟通， 建立互利的机构间伙伴关系， 在癌症相关研究、癌症研究经验和外展教育方面的重点合作。

ABSTRACT – Administrative Core The Southeast Partnership for Improving Research and Training in Cancer Health Disparities (SPIRIT-CHD) unites the Louisiana State University Health Sciences Center (LSUHSC), an institution serving underserved populations and underrepresented students (ISUPS), and the NCI-designated Moffitt Cancer Center (MCC) to advance translational research on the biological mechanisms of cancer health disparities focusing on biospecimen-based research and precision medicine education. The Administrative Core (AC) provides the necessary central oversight, coordination, support and logistics needed to make SPIRIT-CHD function effectively, with ongoing communications and improvements being key responsibilities. To achieve this, the AC has the following objectives: a) oversee planning activities; b) coordinate and monitor the pilot research projects and the cancer research education program; c) foster productive interactions among collaborators, Early Stage Investigators (ESIs), and students; d) monitor progress and conduct evaluations of component sections, e) review and revise short-term and long-range plans on a regular basis; f) ensure the highest standards of scientific integrity for all project and program components and activities, and g) stimulate new research collaborations related to health disparities; and h) ensure integration among the programs and cores. The AC is led by a multidisciplinary team of established investigators, is guided by an Internal Advisory Committee that is comprised of community-academic members, and is highly supported by leadership of both institutions. It synergistically links and builds on our experiences with other PACHE, CURE, and Community Network Partnership Programs.A series of planning and priority-setting steps will be implemented to establish regular and ongoing interactions, in-person retreats, and other communication channels to facilitate: 1) conduct of a pilot research program beginning with a project centered on breast cancer genomics utilizing breast cancer biospecimens from Latina patients of mixed genetic ancestry (African, Native American, European); and 2) implementation of a three-pronged joint Cancer Research Education Program that provides undergraduate and medical students with a hands on summer research experience, delivers a curriculum and focused training to the students on biobanking, precision medicine and cancer health disparities and expands existing outreach education to our respective racial/ethnic minorities communities. Importantly, the AC ensures that guidance and feedback are provided as necessary to achieve partnership goals and integration of SPIRIT-CHD components. Overall, the AC facilitates the coordination and communication necessary for a seamless and mutually beneficial inter-institutional partnership to advance the feasibility, planning and implementation of focused collaborations in cancer-related research, cancer research experience and outreach education.