Core A: Administrative Core

项目总结/摘要 行政核心监督和指导COBRE在肝损伤机制方面的运作， 疾病在堪萨斯大学医学中心。项目主任/主要研究者将是Dr. Hartmut Jaeschke，他是II期的PD/PI。他将得到该计划的协助和建议 协调员Bruno Hagenbuch博士和指导委员会的其他成员， 两个核心，试点赠款项目主任，和高级副院长的研究学院 药外部咨询委员会由五位国际公认的肝脏研究权威组成 还将为COBRE的运行提供指导和建议，并将担任 试点赠款方案。行政核心将监督和指导非常成功的核心实验室 和试点赠款计划，以及提供持续的辅导和职业发展指导 为初级教员。

PROJECT SUMMARY / ABSTRACT The Administrative Core oversees and guides the operation of the COBRE on Mechanisms of Liver Injury and Diseases at the University of Kansas Medical Center. The Program Director/Principal Investigator will be Dr. Hartmut Jaeschke, who was the PD/PI during Phase II. He will be assisted and advised by the Program Coordinator Dr. Bruno Hagenbuch and other members of the Steering Committee consisting of the chairs of the 2 cores, the Pilot Grants Program Director, and the Senior Associate Dean for Research of the School of Medicine. An External Advisory Board comprised of five internationally recognized authorities in liver research will also provide guidance and advice for the COBRE operation and will function as external reviewers for the Pilot Grants Program. The Administrative Core will oversee and guide the highly successful Core Laboratories and the Pilot Grants Program in addition to providing continued mentoring and career development guidance for junior faculty.