Building Trust to Enhance Diversity in Aging Research

ADRD对《建立信任以增强老龄研究多样性》的补充 这项补充建议旨在扩大我们的合作计划的范围， 加强老龄化研究多样性的信托“(R24 AG063728)，以制定一个登记册，反映 未来参与临床老龄化研究的多样化个体群体，通过添加 那些有认知问题和阿尔茨海默病及相关痴呆(ADRD)的人 没有包括在我们的父项目中。在拟议的ADRD补编中，我们试图 了解ADRD患者及其照顾者的特殊关切，作为 将他们登记到发展中的登记处。ADRD占的比例越来越大 在老年人中的死亡人数；在各种风险范围内显示种族和其他差异 因素、诊断和治疗；对家庭和照顾者来说是负担。更多 需要做的工作是了解风险因素、机制和ADRD的过程 在代表性不足的人群中取得进展。通过对个人的结构化采访 轻度认知障碍(MCI)或轻度ADRD，以及他们的照顾者(如果适用)，我们将 试点测试和调整我们的登记处招聘战略遴选程序。我们还将确定 MCI或轻度ADRD患者及其患者参与研究的障碍 照顾者。我们还会将这些障碍与参与者报告的障碍进行比较和对比 没有认知障碍的父母研究。本补充文件的首要目标是 使用类似方法，扩展正在进行的家长研究的工作，使不同的 自愿加入我们的老年人口登记，以便它将包括那些有 认知障碍，包括轻微的ADRD，以及他们的照顾者，从而提高价值 向正在进行老龄化研究的调查人员提供登记资料。

ADRD SUPPLEMENT TO “BUILDING TRUST TO ENHANCE DIVERSITY IN AGING RESEARCH” This supplement proposal seeks to extend the scope of our collaborative program, “Building Trust to Enhance Diversity in Aging Research” (R24 AG063728), to develop a registry reflecting a diverse population of individuals for future participation in clinical aging studies by adding those with cognitive problems and Alzheimer’s disease and related dementias (ADRD) who were not included in our parent project. In the proposed ADRD Supplement we attempt to understand the special concerns of those with ADRD and their caregivers as a first step in enrolling them into the developing registry. ADRD are responsible for an increasing proportion of deaths among older adults; display racial and other disparities across the spectrum of risk factors, diagnosis, and treatment; and are burdensome for families and caregivers. Much more work needs to be done to understand risk factors, mechanisms, and the course of ADRD progression in underrepresented populations. Through structured interviews with individuals with mild cognitive impairment (MCI) or mild ADRD, and their caregivers if applicable, we will pilot test and adapt our registry recruitment strategies selection process. We will also identify barriers to participation in research studies among individuals with MCI or mild ADRD and their caregivers. We will also compare and contrast these barriers with those reported by participants of the parent study without cognitive impairments. The overarching goal of this supplement is to extend, using similar methods, the ongoing parent study’s work in engaging a diverse population of older adults to voluntarily join our registry to so that it will encompass those with cognitive impairments, including mild ADRD, and their caregivers thereby enhancing the value of the registry to investigators conducting aging research.