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中文摘要
翻译
项目摘要: 临床前研究核心(PRC)将为研究者提供集中资源, 彭宁顿生物医学研究中心的疾病代谢基础COBRE模型。中国将 支持动物研究的各个方面,包括实验设计,体内程序的执行, 以及培训使用最先进的设备进行动物表型分析、数据分析和解释, 转基因小鼠品系的使用,以及动物健康和监管领域的一般支持 合规PRC的总体目标是统一和扩展目前支持 将临床前研究转化为一个有凝聚力的团队,有效地指导、培训和支持COBRE研究人员。 考虑到每个COBRE研究项目都利用了临床前模型, 在中国境内的支持和设备应大大提高生产力和创新, 每个研究项目。
英文摘要
Project Summary: The Preclinical Research Core (PRC) will provide a centralized resource for investigators utilizing preclinical models within Pennington Biomedical Research Center’s Metabolic Basis of Disease COBRE. The PRC will support all aspects of animal research, including experimental design, execution of in vivo procedures, access and training in the use of state-of-the-art equipment for animal phenotyping, data analysis and interpretation, use of genetically-modified mouse lines, and general support in areas of animal health and regulatory compliance. The overarching goal of the PRC is to unify and extend existing resources that currently support preclinical research into a cohesive team that effectively mentors, trains and supports COBRE investigators. Considering that each of the COBRE research projects utilizes preclinical models, the mentoring, technical support and equipment housed within the PRC should substantially enhance the productivity and innovation of each research project.
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FGF21-dependent mechanisms driving changes in energy expenditure during dietary protein restriction
Neural circuits coordinating protein intake: Role of FGF21
Preclinical
FGF21-dependent mechanisms driving changes in energy expenditure during dietary protein restriction
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