Preclinical
Preclinical
批准号:
10569511
负责人:
Christopher D Morrison
金额:
$40.49万
依托单位国家:
美国
项目类别:
财政年份:
2020
资助国家:
美国
项目状态:
未结题
起止时间:
2020-03-01 至 2025-01-31
关键词:
AccelerationAnimal ExperimentationAnimal ModelAnimalsAreaAwardBehavioralBiomedical ResearchCenters of Research ExcellenceCommunitiesData AnalysesDevelopmentDiseaseDisparateEnsureEnvironmentEquipmentExperimental DesignsFacultyGenetic ModelsGoalsHealthInfrastructureKnowledgeLaboratoriesMentorsMetabolicMetabolic DiseasesMethodologyMissionMusOperative Surgical ProceduresPhenotypePre-Clinical ModelProceduresProductivityReproducibilityResearchResearch PersonnelResearch Project GrantsResourcesScientistTechniquesTestingTissue BanksTrainingWorkcareerexperienceexperimental analysisexperimental studyhuman diseasehuman modelin vivoinnovationmetabolic phenotypenovelpre-clinicalpre-clinical researchprotocol developmentresearch facultyskillssupportive environment
中文摘要
项目摘要:
临床前研究核心(PRC)将为研究者提供集中资源,
彭宁顿生物医学研究中心的疾病代谢基础COBRE模型。中国将
支持动物研究的各个方面,包括实验设计,体内程序的执行,
以及培训使用最先进的设备进行动物表型分析、数据分析和解释,
转基因小鼠品系的使用,以及动物健康和监管领域的一般支持
合规PRC的总体目标是统一和扩展目前支持
将临床前研究转化为一个有凝聚力的团队,有效地指导、培训和支持COBRE研究人员。
考虑到每个COBRE研究项目都利用了临床前模型,
在中国境内的支持和设备应大大提高生产力和创新,
每个研究项目。
英文摘要
Project Summary:
The Preclinical Research Core (PRC) will provide a centralized resource for investigators utilizing preclinical
models within Pennington Biomedical Research Center’s Metabolic Basis of Disease COBRE. The PRC will
support all aspects of animal research, including experimental design, execution of in vivo procedures, access
and training in the use of state-of-the-art equipment for animal phenotyping, data analysis and interpretation,
use of genetically-modified mouse lines, and general support in areas of animal health and regulatory
compliance. The overarching goal of the PRC is to unify and extend existing resources that currently support
preclinical research into a cohesive team that effectively mentors, trains and supports COBRE investigators.
Considering that each of the COBRE research projects utilizes preclinical models, the mentoring, technical
support and equipment housed within the PRC should substantially enhance the productivity and innovation of
each research project.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
FGF21-dependent mechanisms driving changes in energy expenditure during dietary protein restriction
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批准号:10359751
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项目类别:
-
资助金额:$37.0万
-
财政年份:2020
-
负责人:Christopher D Morrison
-
依托单位:
Neural circuits coordinating protein intake: Role of FGF21
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批准号:10263297
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项目类别:
-
资助金额:$33.3万
-
财政年份:2020
-
负责人:Christopher D Morrison
-
依托单位:
Preclinical
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批准号:10333352
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项目类别:
-
资助金额:$31.29万
-
财政年份:2020
-
负责人:Christopher D Morrison
-
依托单位:
FGF21-dependent mechanisms driving changes in energy expenditure during dietary protein restriction
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批准号:10578837
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项目类别:
-
资助金额:$37.0万
-
财政年份:2020
-
负责人:Christopher D Morrison
-
依托单位:
FGF21-dependent mechanisms driving changes in energy expenditure during dietary protein restriction
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批准号:10161777
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项目类别:
-
资助金额:$37.0万
-
财政年份:2020
-
负责人:Christopher D Morrison
-
依托单位:
Neural circuits coordinating protein intake: Role of FGF21
-
批准号:10662472
-
项目类别:
-
资助金额:$33.3万
-
财政年份:2020
-
负责人:Christopher D Morrison
-
依托单位:
Neural circuits coordinating protein intake: Role of FGF21
-
批准号:10449404
-
项目类别:
-
资助金额:$33.3万
-
财政年份:2020
-
负责人:Christopher D Morrison
-
依托单位:
FGF21-dependent mechanisms driving changes in energy expenditure during dietary protein restriction
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批准号:9973291
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项目类别:
-
资助金额:$37.0万
-
财政年份:2020
-
负责人:Christopher D Morrison
-
依托单位:
Sable Systems Promethion for Mouse Metabolic Analysis
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批准号:9281302
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项目类别:
-
资助金额:$62.58万
-
财政年份:2017
-
负责人:Christopher D Morrison
-
依托单位:
FGF21 is an endocrine signal of protein restriction
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批准号:9388340
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项目类别:
-
资助金额:$33.3万
-
财政年份:2015
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负责人:Christopher D Morrison
-
依托单位:
FGF21 is an endocrine signal of protein restriction
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批准号:9274081
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项目类别:
-
资助金额:$3.45万
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财政年份:2015
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负责人:Christopher D Morrison
-
依托单位:
Neural regulation of protein ingestion
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批准号:7785633
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项目类别:
-
资助金额:$33.3万
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财政年份:2010
-
负责人:Christopher D Morrison
-
依托单位:
LOUISIANA COBRE: P4: MECHANISMS OF AGING-INDUCED LEPTIN RESISTANCE AND OBESITY
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批准号:8167952
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项目类别:
-
资助金额:$20.58万
-
财政年份:2010
-
负责人:Christopher D Morrison
-
依托单位:
Neural regulation of protein ingestion
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批准号:8049740
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项目类别:
-
资助金额:$28.52万
-
财政年份:2010
-
负责人:Christopher D Morrison
-
依托单位:
Neural regulation of protein ingestion
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批准号:8664366
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项目类别:
-
资助金额:$27.49万
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财政年份:2010
-
负责人:Christopher D Morrison
-
依托单位:
Neural regulation of protein ingestion
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批准号:8468686
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项目类别:
-
资助金额:$26.54万
-
财政年份:2010
-
负责人:Christopher D Morrison
-
依托单位:
Neural regulation of protein ingestion
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批准号:8280397
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项目类别:
-
资助金额:$27.52万
-
财政年份:2010
-
负责人:Christopher D Morrison
-
依托单位:
LOUISIANA COBRE: P4: MECHANISMS OF AGING-INDUCED LEPTIN RESISTANCE AND OBESITY
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批准号:7959987
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项目类别:
-
资助金额:$23.41万
-
财政年份:2009
-
负责人:Christopher D Morrison
-
依托单位:
LOUISIANA COBRE: P4: MECHANISMS OF AGING-INDUCED LEPTIN RESISTANCE AND OBESITY
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批准号:7720514
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项目类别:
-
资助金额:$21.13万
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财政年份:2008
-
负责人:Christopher D Morrison
-
依托单位:
LOUISIANA COBRE: P4: MECHANISMS OF AGING-INDUCED LEPTIN RESISTANCE AND OBESITY
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批准号:7610784
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项目类别:
-
资助金额:$20.96万
-
财政年份:2007
-
负责人:Christopher D Morrison
-
依托单位:
海外基金