Pilot Project Program

摘要 试点项目计划是EDGE中心的一个组成部分，为调查人员提供初步支持 建立与NIEHS和EDGE中心的任务相关的新的研究路线。该计划 促进探索可能的创新方向，与正在进行的方向有很大的不同 资助环境健康科学研究人员的研究。来自其他重点领域的调查人员包括 还鼓励将其专业知识应用于环境健康研究。试点项目的补助金是 旨在帮助调查人员获得有助于竞争性全面拨款的初步数据 在基因-环境相互作用(GxE)领域的应用。该中心特别鼓励申请 侧重于人类遗传和表观遗传变异作为环境诱导的修饰者的作用 疾病。这些赠款还可侧重于以研究为基础的社区外联活动。边缘飞行员 项目计划是一个很好的工具，可以培养新的有趣的假设，旨在填补EHS的空白 研究，特别是与环境暴露、机械毒理学和基因-环境有关的研究 互动。该中心致力于为许多人的职业生涯提供宝贵的支持 通过试点项目计划培养有前途的年轻科学家。因此，该计划将有利于 申请初级EHS教员，并利用这一计划，以加强他们的职业发展。 这一计划已经并将继续是中心作为一个 完整的。

ABSTRACT The Pilot Project Program is an integral part of the EDGE Center, providing initial support for investigators to establish novel lines of research relevant to the missions of the NIEHS and the EDGE Center. The program promotes exploration of possible innovative directions representing a significant departure from on-going funded research for investigators in environmental health sciences. Investigators from other areas of focus are also encouraged to apply their expertise to environmental health research. The pilot project grants are designed to assist investigators in obtaining preliminary data that will be useful for competitive, full-scale grant applications in the area of gene-environment interaction (GxE). The Center especially encourages applications that focus on the role of human genetic and epigenetic variation as modifiers of environmentally induced diseases. These grants may also focus on research-based community outreach activities. The EDGE Pilot Projects Program serves as a great tool to foster new and interesting hypotheses that aim to fill gaps in EHS research, especially in relation to environmental exposures, mechanistic toxicology and gene-environment interactions. The Center is committed to providing invaluable support in launching the careers of a number of promising young scientists through the Pilot Projects Program. Therefore, the program will favor the applications of junior EHS faculty members and utilize this program to augment their Career Development. This program has and will continue to be imperative to the interconnectedness and success of the Center as a whole.