Administrative Core

行政核心（AC）：摘要 环境毒理学卓越中心（CEET）的行政核心（AC）位于 两名经验丰富的调查人员的有效领导与赋予椅子：特雷弗潘宁，博士（塞尔玛布朗 和亨利查尔斯莫利诺夫药理学教授）和丽贝卡A.西蒙斯，医学博士（哈勒姆伤害赋予 儿科教授）。他们确保CEET战略愿景的目标得以实现。 在机构、区域和国家层面提升CEET的环境健康特性， 在CEET主题领域内和跨CEET主题领域促进团队科学。AC引导形成灵活的 主题领域，目前在：空气污染和肺部健康，环境暴露和癌症， 敏感窗口和环境神经科学。致力于这些主题的调查人员 在各自领域享有国际声誉的领导人。AC监督综合 健康科学设施核心（IHSFC）、转化生物标志物核心（TBC）和暴露生物学 信息学核心（EBIC），以确保它们满足专题领域和CEET调查员的需求。的 AC鼓励与社区参与核心的沟通，互动，参与和交流 (CEC)将社区关注的问题提请专题领域调查人员和IHSFC注意。评价 决策过程的指导由四个委员会监督，即内部咨询委员会， 执行委员会、董事理事会和外部咨询委员会。报告和财政 管理由经验丰富的中心管理员和赠款经理提供支持。一个核心组成部分 AC的目的是培养早期研究人员（ESI）的职业生涯，使他们成为下一代 环境健康（EH）科学家我们的理念是，环境健康科学是独一无二的， 生物医学科学，因为它跨越了从机械毒理学， 流行病学、暴露科学以及向患者、社区和政策制定者的转化。此外，本发明还提供了一种方法， 成功的EH科学家越来越多地面临“大数据”，以及如何将这些数据转化为知识 这需要熟悉生物信息学工具和计算科学的进展， 机器学习和AI。我们的环境健康科学家支持计划旨在提供一个 变革性的经验，使我们的ESI将配备成功的工具，作为下一代 EHS科学家咨询委员会还通过让高级调查员进入CEET来建设能力， 这是他们职业生涯中第一次解决环境健康问题。以这种方式，AC响应于NIEHS 战略计划强调资源管理和建立专业人才管道。

ADMINISTRATIVE CORE (AC) : ABSTRACT The Administrative Core (AC) of the Center of Excellence in Environmental Toxicology (CEET) is under the effective leadership of two seasoned investigators with endowed chairs: Trevor Penning, PhD (Thelma Brown and Henry Charles Molinoff Professor of Pharmacology) and Rebecca A. Simmons, MD (Hallam Hurt Endowed Professor in Pediatrics). They ensure that the goals of the CEET strategic vision are achieved This vision elevates the environmental health identity of the CEET at the institutional, regional, and national levels and promotes team science within and across the CEET thematic areas. The AC guides the formation of flexible thematic areas, which currently are in: Air Pollution & Lung Health, Environmental Exposures & Cancer, Windows-of-Susceptibility, and Environmental Neuroscience. Investigators committed to these themes are led by leaders of international repute in their respective areas. The AC provides oversight to the use of the Integrative Health Sciences Facility Core (IHSFC), the Translational Biomarker Core (TBC) and the Exposure Biology Informatics Core (EBIC) to ensure they address the needs of the thematic areas and the CEET investigator. The AC encourages communication, interaction, involvement and exchange with the Community Engagement Core (CEC) to bring community concerns to the attention of thematic area investigators and the IHSFC. Evaluation and guidance in decision making processes is overseen by four committees, the Internal Advisory Committee, the Executive Committee, the Directors Council and the External Advisory Board. Reporting and fiscal management are supported by an experienced Center Administrator and Grants Manager. A central component of the AC is to cultivate the careers of Early-Stage Investigators (ESI) to establish them as the next generation of environmental health (EH) scientists. Our philosophy is that environmental health science is unique among the biomedical sciences since it spans diverse interdisciplinary expertise ranging from mechanistic toxicology, epidemiology, exposure science, and translation to patients, communities, and policy makers. In addition, successful EH scientists are increasingly faced with “Big-Data”, and how to transform such data into knowledge which requires familiarity with bioinformatics tools and the advances being made in computational science, machine learning and AI. Our Environmental Health Scientist Support Program is designed to provide a transformative experience so that our ESI will be equipped with the tools for success as the next generation of EHS scientists. The AC also builds capacity by bringing senior investigators into the CEET who are addressing environmental health problems for the first time in their careers. In this manner the AC is responsive to the NIEHS strategic plan which stresses stewardship of resources and building the professional pipeline.