Translational Research Training Program in Environmental Health Sciences

环境健康科学转化研究培训计划

• 批准号: 9279452
• 负责人: Trevor M Penning
• 金额: $ 39.97万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9279452
• 关键词: Environmental Health; Training Programs; Translational Research

This application is the first competing continuation of a T32 Institutional Training Grant in Environmental Health Sciences (EHS) entitled: “Translational Research Training Program in EHS” (T32-ES019851) at the University of Pennsylvania (Penn). This training grant is the only dedicated mechanism to support formalized EHS research training at the pre- and post-doctoral level at Penn and meets a significant need based on trainee interest in the environment and its health impact and biomedical work force need. The mission of the T32 Training Program is to train the next generation of environmental health scientists in the mechanisms by which environmental exposures cause disease and to translate these findings into effective prevention and treatment and improvements in public health. The training program emphasizes the four pillars of translational research, bench, bedside, community and policy. The research training reflects the translational research themes of Penn's P30 Environmental Health Sciences Core Center, the Center of Excellence in Environmental Toxicology (CEET). These themes have been dictated by the incidence of disease that have environmental etiology that affect the Philadelphia region, the physical location of Penn. Training is provided through course work from the Certificate Program in EHS which includes an optional Community Environmental Health Rotation, by conducting a full-time translational research project co- mentored where possible by a basic-scientist and clinician scientist to generate new knowledge in EHS. The 42 distinguished training grant faculty come from Penn and Children's Hospital of Philadelphia and 14 are clinician scientists. The training grant supports common elements including a research club, a dedicated seminar series, an annual symposium dedicated to a translational research theme and optional externships at US EPA, ATSDR and the Silent Spring Institute for trainees interested in policy and human health assessment. The T32 award currently supports three predoctoral fellows to conduct dissertation research on an EHS topic and four postdoctoral fellows to perform mentored EHS research. Predoctoral trainees are supported for a total of three years (2nd year completion of the Certificate Program in EHS and two years dissertation research) and postdoctoral trainees are supported for up to two years. Trainees will be prepared for a suite of careers in the employment sector e.g. academia (in EHS, Pharmacology and Toxicology), government agencies (e.g. US- EPA, CDC, FDA, NTP, NIEHS); and industry (drug, food, cosmetic and nanotechnology). Fifteen trainees were supported in the first four years of this training program and published 41 papers; all the postdoctoral fellows that have left the program have assumed faculty positions. In the next cycle of funding we request an identical number of predoctoral (3) and postdoctoral slots (4).

该申请是 T32 环境健康机构培训补助金的第一个竞争性延续 科学（EHS），题为：“EHS 转化研究培训计划”（T32-ES019851） 宾夕法尼亚大学（宾夕法尼亚大学）。该培训补助金是支持正规化的唯一专门机制 宾夕法尼亚大学博士前和博士后级别的 EHS 研究培训，满足基于以下方面的重大需求： 学员对环境及其健康影响和生物医学劳动力需求的兴趣。的使命 T32培训计划旨在培养下一代环境健康科学家 环境暴露导致疾病的机制并将这些发现转化为 有效预防和治疗，改善公共卫生。培训计划强调 转化研究的四大支柱：实验室、临床、社区和政策。研究培训体现 宾夕法尼亚大学 P30 环境健康科学核心中心、该中心的转化研究主题 环境毒理学卓越奖 (CEET)。这些主题是由发生率决定的 具有影响费城地区（宾夕法尼亚州物理位置）的环境病因的疾病。 培训通过 EHS 证书计划的课程作业提供，其中包括可选的课程 社区环境健康轮换，通过开展全职转化研究项目共同 尽可能由基础科学家和临床科学家指导，以产生 EHS 方面的新知识。这 42 名杰出培训资助教师来自宾夕法尼亚大学和费城儿童医院，其中 14 名是 临床科学家。培训补助金支持共同要素，包括研究俱乐部、专门的 研讨会系列，每年一次的研讨会，致力于转化研究主题和可选的实习 US EPA、ATSDR 和 Silent Spring Institute 为对政策和人类健康评估感兴趣的学员提供培训。 T32 奖项目前支持三名博士前研究员进行 EHS 主题的论文研究 和四名博士后研究员进行指导的 EHS 研究。博士前培训生获得的资助总额为 三年（第二年完成 EHS 证书课程和两年论文研究）以及 博士后培训生的支持期限最长为两年。学员将为在该领域的一系列职业做好准备 就业部门，例如学术界（EHS、药理学和毒理学）、政府机构（例如美国- EPA、CDC、FDA、NTP、NIEHS）；和工业（药品、食品、化妆品和纳米技术）。十五名实习生 该培训项目的前四年得到了支持，并发表了 41 篇论文；所有博士后 离开该项目的研究员已担任教职。在下一个资助周期中，我们要求 博士前（3）和博士后名额（4）数量相同。