Molecular Biology in Burns and Trauma

Ruth Kirschstein NRSA培训计划建议主要采取外科医生和其他危重护理 在他们的普通住院医师计划的第二年或第三年，并让他们接触到 在炎症生物学方面进行了两年、三年甚至四年的指导研究，基础科学成果丰硕 导师们专注于与炎症相关的话题。需要四个培训职位。整体研究 该计划将侧重于掌握分子生物学、功能基因组学和基因调控，因为它应用 泛指炎症研究。尽管培训计划的大部分将在一个 经验丰富的研究导师，学员将被期望参加与之相辅相成的教学经验 他们的研究经验。被选中的实习生将有机会完成研究生的博士课程 三到四年后就可以上学了。其他学员可以参加正式的研究生证书课程。 通过一个学术单位提供的课程集合，这些课程共同构成一个连贯的学习计划。这 培训计划利用医学院在不断扩大的领域的独特优势 功能基因组学和分子生物学，以及基础科学家和 临床医师致力于培养未来的临床院士。分子生物学和分子生物学之间的接口 炎症研究将针对创伤、脓毒症综合征、缺血/再灌注损伤、血管损伤、 延迟伤口愈合和烧伤创面。教员将从获得资助的基础和临床科学家中挑选出来。 外科、医学、病理学、老年学和老年学研究以及分子遗传学和微生物学 他们将担任受训人员的研究导师。来自外科、医学的临床导师 病理学系将与学员和研究人员互动，以确保学员 在炎症研究中接触到临床上重要的问题。该计划的总体方向将 由项目主管和执行委员会负责。该奖学金的候选人已被招募 来自全国和佛罗里达大学医学院(盖恩斯维尔，杰克逊维尔)。成功 执行委员会的申请者将确定一名研究和临床导师，他将帮助制定 正式的培训计划和定期审查受训人员的进度。此外，预计受训人员将 参加老龄研究所、新病原体研究所和遗传学研究所的基础科学研讨会 在研究所，以及在自己的基础科学部门，以及实验室研究会议。他们也将成为 预计将参加临床研讨会，包括外科和危重护理医学大查房和 外科学术研究会议。根据我们过去的经验，预计 这一培训计划的成功毕业生将拥有足够的研究技能，以成功竞争 在炎症研究方面提供过渡性资金，并成为学术外科领域的领导者。

This Ruth Kirschstein NRSA training Program proposes to take primarily surgeons and other critical care medicine physicians during the second or third year of their general residency programs, and expose them to two, three and even four years of mentored research in inflammation biology with highly productive basic science mentors focused on inflammation‐related topics. Four training positions are requested. The overall research program will focus on mastery of molecular biology, functional genomics and gene regulation, as it applies broadly to inflammation research. Although the bulk of the training program will be in the laboratory of an experienced research mentor, trainees will be expected to participate in didactic experiences that complement their research experience. Select trainees will have the opportunity to complete a Ph.D. program in the Graduate School in three to four years. Other trainees can participate in graduate certificate programs which are formal collections of courses that together form a coherent program of study offered through an academic unit. This training program takes advantage of the unique strengths of the College of Medicine in the expanding field of functional genomics and molecular biology, as well as the existing collaborations between basic scientists and clinicians committed to the training of future clinical academicians. The interface between molecular biology and inflammation research will be targeted to trauma, sepsis syndromes, ischemia/reperfusion injury, vascular injury, delayed wound healing and the burn wound. The faculty will be drawn from funded basic and clinical scientists in the Surgery, Medicine, Pathology, Aging and Geriatric Research and Molecular Genetics and Microbiology Departments, who will serve as research mentors to the trainees. Clinical mentors from the Surgery, Medicine and Pathology Departments will interact with the trainees and the research faculty to assure that the trainees are being exposed to clinically‐important issues in inflammation research. Overall direction of the program will rest with the Program Director and an Executive Committee. Candidates for the fellowship are recruited nationally and from the University of Florida College of Medicine (Gainesville, Jacksonville). Successful applicants with the Executive Committee will identify a research and clinical mentor who will help formulate a formal training program and periodic review of the trainee’s progress. Furthermore, trainees are expected to participate in basic science seminars in the Institute on Aging, Emerging Pathogens Institute and Genetics Institute, and in their own basic science departments, as well as laboratory research meetings. They will also be expected to attend clinical seminars, including Surgery and Critical Care Medicine Grand Rounds and the Department of Surgery Academic Research Conference. Based on our past experiences, it is anticipated that successful graduates of this training program will possess sufficient research skills to successfully compete for transitional funding in inflammation research and become leaders in academic surgery.