North Carolina Translational and Clinical Sciences Institute (NC TraCS)

项目摘要 北卡罗来纳州转化和临床科学研究所（TraCS）是一个充满活力的区域网络， 大学、研究机构、医疗保健提供者和全州250多个社区合作者。 TraCS总部设在美国查佩尔山，与美国最大的HBCU NC A&T建立了战略合作伙伴关系。 美国，它带来了健康公平研究、劳动力发展、工程和数据方面的专业知识， 科学，北卡罗来纳州，拥有全国排名的兽医学院和其他专业知识， 工程和计算机科学。在接下来的七年里，我们将促进开发，测试， 实施和传播转化科学和研究，以改善人类健康， 通过完成我们的总体目标，明确关注促进卫生公平。目标1：执行和支持 研究，推进翻译科学的目标是清除障碍，以快速翻译 为我们的患者及其社区提供最佳证据。目标2：最大化 转化研究的信息量，以推动其影响，以提高临床受益并减少危害， 特别关注受卫生不平等影响的人群。目标3：培养和保持一个多元化的，专家， 在所有专业水平的多学科翻译研究队伍，准备迎接挑战， 当前和未来的健康危机。目标4：实施循证战略，利用 我们的学习保健系统作为我们的实验室。 我们认识到， 这些都是有效地将创新转化为健康的关键障碍。我们将利用（i） 我们学习医疗保健系统的大量资源，以及（ii）TraCS经过磨练的集体专业知识 14年来支持世界一流的转化研究，将社会正义的原则融入我们所有的课程中。 服务和培训，并实现我们的愿景“一个更健康的北卡罗来纳州通过创新”。我们将 创新包容性的方法和流程，建立信任，并招募能够反映 我们国家的多样性。我们将实施我们的进步，以确保我们的参与者，他们的社区的利益 到处都是病人。通过广泛的利益相关者参与和对我们工作的严格评估，我们将 最大限度地提高我们的研究对我们所服务的人的相关性。TraCS将领导和支持整个 CTSA联盟致力于创造一个更有效、更具包容性的研究环境，以减轻健康差距。

Project Summary The North Carolina Translational and Clinical Sciences Institute (TraCS) is a dynamic regional network of universities, research institutes, healthcare providers, and >250 community collaborators across our state. Based at UNC Chapel Hill, TraCS has strategically fostered partnerships with NC A&T, the largest HBCU in the U.S., which brings expertise in health equity research, workforce development, engineering, and data science, and NC State, with a nationally ranked school of veterinary medicine and additional expertise in engineering and computer science. Over the next seven years, we will catalyze development, testing, implementation, and dissemination of translational science and research to improve human health, with an explicit focus on advancing health equity by completing our Overall Aims. Aim 1: Perform and support research that advances the science of translation with the goal of clearing barriers to rapid translation of research towards implementation of best evidence to our patients and their communities. Aim 2: Maximize the informativeness of translational research, to drive its impact to improve clinical benefits and reduce harms with particular attention to populations impacted by health inequities. Aim 3: Train and maintain a diverse, expert, multidisciplinary translational research workforce at all professional levels, prepared to meet the challenges of current and future health crises. Aim 4: Implement evidence-based strategies to improve human health using our learning health care system as our laboratory. We have intensified our efforts in health equity as well as dissemination and implementation, recognizing that these are the critical barriers to effective translation of innovation to health. We will capitalize on (i) the substantial resources of our learning health care system and (ii) the collective expertise of TraCS, honed over 14 years of supporting world-class translational research, to integrate the principles of social justice in all our services and trainings and to realize our vision of “A healthier North Carolina through innovation”. We will innovate inclusive methods and processes, engender trust, and recruit research participants who reflect the diversity of our state. We will implement our advances to ensure benefits for our participants, their communities and patients everywhere. With broad stakeholder engagement and rigorous evaluation of our efforts, we will maximize the relevance of our research to those we serve. TraCS will lead and support efforts across the CTSA consortium to create a more efficient, inclusive research environment to mitigate health disparities.