Nebraska Research Network in Functional Genomics

生物信息学核心 项目摘要 生物信息学核心在NE-INBRE项目的全面成功中发挥了关键作用，它通过促进 获得资源、技术和服务，并为网络成员提供使用 生物信息学中的计算和数据分析工具。在过去的五年中，使用了高吞吐量的 包括下一代测序(NGS)在内的技术已经成为NE-INBRE的常见技术 调查人员。因此，对开发计算和生物信息学有着巨大的需求 用于收集、处理、存储和分析大规模数据集的基础设施。具有并行功能 不断变化的实验技术、新的生物信息学算法和工具的发展需要 开发或采用，以满足研究界日益增长的数据分析需求。鉴于...的性质 这种复杂性，对于个别机构来说，在当地发展和维护尖端技术是极具挑战性的 生物信息学方面的基础设施和技术专长。这个生物信息学核心的主要目标是开发 这样的环境、技术、工具和服务，并使其可供NE-INBRE中的所有成员访问 网络。核心项目的主要目标包括为未来需求开发尖端基础设施 在继续支持和培训东北非洲研究所学者和研究人员利用资源和 技术。生物信息学核心将配备以提供所需的基础设施、获取资源、 为NE-INBRE网络成员提供技术支持、教育和指导机会。

Bioinformatics Core Project Summary The Bioinformatics Core has served as a key player in the overall success of the NE-INBRE project by facilitating access to resources, technology, services, and providing training to the network members in the use of computational and data analysis tools in bioinformatics. Over the past five years, the use of high-throughput technologies including next-generation sequencing (NGS) has become a commonplace by the NE-INBRE investigators. Consequently, there has been a tremendous need for developing computational and bioinformatic infrastructure for the collection, processing, storage, and analysis of large-scale datasets. With parallel developments in the ever-changing experimental technologies, new bioinformatic algorithms and tools need to be developed or adopted to meet the growing data analysis needs of the research community. Given the nature of this complexity, it is extremely challenging for individual institutions to locally develop and maintain sophisticated infrastructure and technical expertise in bioinformatics. The primary goal of this Bioinformatics Core is to develop such environment, technology, tools, and services and make them accessible to all members in the NE-INBRE network. The main objectives of the Core include the development of cutting-edge infrastructure for future needs while continuing to support and train NE-INBRE Scholars and investigators in the use of resources and technologies. The Bioinformatics Core will be equipped to provide the needed infrastructure, access to resources, technical support, education and mentoring opportunities for the NE-INBRE network members.