Mechanisms Underlying Individual Variations of Taste and Smell in Obesity

这项经irb批准的研究比较了肥胖和非肥胖个体的味觉和嗅觉测量。将评估味觉和嗅觉对食物摄入和选择的影响。我们假设肥胖会对味觉和嗅觉产生负面影响，从而影响饮食行为。我们将招募124名按年龄和性别匹配的肥胖者和124名健康非肥胖者作为对照。参与者将从华盛顿大都会区及周边地区招募。这项研究将在美国国立卫生研究院临床中心进行。该研究预计将在60个月内完成，从入学开始到研究完成，包括数据分析。本研究包括一次筛选访问和两次研究访问。筛选访问将持续约4-5小时。参观1及2需时约4-6小时。

This IRB-approved study compares taste and smell measures between obese and non-obese individuals. Taste and smell perceptions will be assessed regarding their influence on food intake and choices. We hypothesize that obesity negatively affects taste and smell perception, thus affecting eating behavior. We will recruit a cohort of 124 obese individuals matched by age and sex with 124 healthy non-obese controls. Participants will be recruited from the Washington Metropolitan area and vicinity. This study will take place at the NIH Clinical Center. The study is expected to be completed in 60 months from the opening of enrollment to study completion, including data analysis. This study involves one screening visit and 2 study visits. The screening visit will last approximately 4-5 hours. Visits 1 and 2 will take about 4-6 hours each to be compelted. Currently enrolling