FEASIBILITY OF A LABORATORY MODEL FOR NOCTURNAL BRUXISM

夜间磨牙症已被牵连作为一个病因，在牙齿 磨损，咀嚼肌疼痛，TM条件和某些头痛。 这一重要临床领域的研究进展一直困难重重 由于单桅帆船实验室研究的费用和有限的数据， 其可以使用患者家中的移动记录器来获得。 需要更多的研究途径。本研究的目的 是测试开发一个实验室模型的可行性， 研究夜间磨牙症。第一步和具体目标 这项提议是为了确定清醒的受试者是否可以自愿执行 夜间磨牙症的肌肉收缩模式，如果 所以，为了描述这种行为的本质。 磨牙症活动的肌电图模式将被记录， 在睡眠实验室中， 每人住两晚。一醒来。受试者将尝试模拟 振幅夜间睡眠的持续时间和侧向模式 肌电图活动这种建模将通过可视化 颌部肌肉的EMB生物反馈。此外，还将向受试者提供 对目标的逐步逼近的言语强化 行为 长期目标是发展实验室模型来研究 肌肉和关节疾病的生物力学和病理生理学， 与夜间磨牙症有关最终，目标是提供 了解和临床管理所需的知识 夜间磨牙症和相关的口腔疾病。

Nocturnal bruxism has been implicated as an etiological factor in tooth wear, masticatory muscle pain, TM conditions and certain headaches. Research progress in this important clinical area has been difficult because of the expense of sloop laboratory studies and the limited data which can be obtained using ambulatory recorders in the patients homes. Additional research avenues are necessary. The purpose of this research is to test the feasibility to developing a laboratory model using awake humans to study nocturnal bruxism. The first step and the specific aim of this proposal is to determine if awake subjects can voluntarily perform muscular contraction patterns characteristic of nocturnal bruxism and, if so, to provide a descriptive account of the nature of this behavior. Electromyographic patterns of bruxism activities will be recorded from the jaw muscles in ten chronic bruxist subjects in a sleep laboratory for two night each. Upon waking. subjects will attempt to model the amplitude. duration and lateral patterning of the nocturnal electromyographic activity. This modeling will be facilitate by visual EMB biofeedback from the jaw muscles. In addition, subjects will be given verbal reinforcement for successive approximations of the target behavior. The long-rang goal is to develop laboratory model to study the biomechanics and pathophysiology of muscular and joint conditions which are related to nocturnal bruxism. Ultimately, the goal is to provide knowledge necessary for the understanding and clinical management of nocturnal bruxism and related oral conditions.