Chemsitry Support Services to ETP for Nanotechnology

NTP的另一项举措是研究纳米级材料、富勒烯，这对包括药物输送在内的许多用途都有意义，以及纳米级二氧化钛，用于防晒和增白剂。 这些化合物的特征在于特别注意颗粒尺寸和表面特性。为了支持即将进行的90天灌胃研究，正在进行C60富勒烯的纯度分析。 用于分析小鼠血浆、肝脏、肺、肾脏和肠道组织的方法开发正在进行中。 一种提取方法也在优化过程中。 Eusolex T-2000、T-ECO和T-AVO的剂量分析已经完成。 这包括制备用于FDA/NTCR研究的Eusolex和二氧化钛制剂。 已完成NCTR提供的不同批次二氧化钛的X射线衍射分析。 设计该分析以确定二氧化钛的晶体状态。 经测定，其中两批为金红石型，其余三批为金红石型。

Another NTP initiative are the studies of nanoscale materials, fullerenes, which are of interest for many uses including drug delivery, and nanoscale titanium dioxide, which is used in sunscreen and whitening agents. These compounds characterized with specific attention paid to particle size and surface characteristics. In support of an upcoming 90-day gavage study, purity analysis is in progress of the C60 fullerene. Method development for the analysis of mouse plasma, liver, lung, kidney, and gut tissues are in progress. An extraction method is also in the process of being optimized. Analysis of the doses for the Eusolex T-2000, T-ECO, and T-AVO has been completed. This includes preparation of formulations of the Eusolex and Titanium Dioxide for FDA/NTCR study. X-ray Diffraction analysis of the various lots of Titanium dioxide provided by NCTR has been completed. This analysis was designed to determine the crystal state of the titanium dioxide. It was determined that two of lots were rutile and the other three were anatase.