Translational Research in Cancer

描述(由申请人提供)：这项关于癌症中心支持拨款(CCSG)的提案要求提供资金，以支持基梅尔癌症中心(KCC)的癌症研究活动，以通过将基础研究发现转化为预防、诊断、监测和治疗人类癌症的新策略来提高癌症患者的存活率和生活质量。坎摩尔癌症中心的主要任务是发现癌症遗传学、细胞生物学、生物化学和免疫学的最新发现，并将其转化为治疗癌症的新方法。 坎摩尔癌症中心由6个项目和13个共享资源组成，以支持这些研究项目。每个项目的研究人员都参与了方案内和方案间的合作，并在为这些合作研究获得同行评审的资金方面取得了极其成功的成果。KCC内的环境促进了许多合作研究和出版物，这些研究和出版物为癌症研究的重要进展做出了贡献。 KCC项目得到了赞助资金的支持。资金来自NCI赞助的73个项目，包括2个方案间NCI计划项目赠款。主任及其招募人员的努力增加了对慈善大学和医院的支持。托马斯·杰斐逊大学癌症研究和护理的重要性体现在该研究所主任对临床和研究活动的权力上，该研究所的面积为144,208平方英尺。英国《金融时报》，以及新设施的建设(232,114平方米包括新的乳房中心、肿瘤学中心和研究空间。这些新设施将容纳KCC调查人员的基本、临床和翻译工作。这些新的KCC设施将进一步加强基梅尔癌症中心的翻译癌症研究工作。

DESCRIPTION (provided by applicant): This proposal for a Cancer Center Support Grant (CCSG) requests funding to support the cancer research activities of the Kimmel Cancer Center (KCC), in order to increase the survival and quality of life of cancer patients by translating basic research discoveries into new strategies to prevent, diagnose, monitor and cure human cancer. The major thrust of the Kimmel Cancer Center is in discovery and translation of the latest findings in the genetics, cell biology, biochemistry and immunology of cancer into novel modalities to cure cancer. The Kimmel Cancer Center consists of six programs and thirteen shared resources to support the research programs. Investigators in each program are involved in intra-programmatic and inter-programmatic collaborations and have been extremely successful in obtaining peer-reviewed funding for these collaborative studies. The environment within the KCC has facilitated numerous collaborative studies and publications that have contributed to important advances in cancer research. The KCC programs are supported by sponsored funding. Funding comes from 73 NCI sponsored projects, including 2 inter-programmatic NCI program project grants. The efforts of the Director and his recruits have resulted in increased philanthropic University and Hospital support. The importance of cancer research and care at Thomas Jefferson University is reflected in the Director's authority over clinical and research activities at the Institution, encompassing 144,208 sq. ft, and the construction of new facilities (232,114 sq. ft) including the new Breast Center, Oncology Center and research space. These new facilities will accommodate the basic, clinical and translational efforts of the KCC investigators. These new KCC facilities will enhance even further the translational cancer research effort of the Kimmel Cancer Center.