Cancer Center Support Grant (Comprehensive)

描述（由申请人提供）：弗雷德哈钦森/华盛顿大学癌症联盟（联盟），成立于2002年，是一个合作伙伴关系：弗雷德哈钦森癌症研究中心，自1976年以来的NCI指定的综合癌症中心和CCSG赠款收件人自1973年以来;华盛顿大学;和儿童医院和区域医疗中心。该联盟汇集了400多名教师，他们对与癌症相关的基础，临床和公共卫生科学感兴趣，NCI总资金为7300万美元（直接费用）。该联盟的目标是通过更有效的预防，诊断和治疗来消除癌症，这源于对疾病生物学的基本见解。这三个机构在基础、临床和公共卫生科学的癌症研究学科之间广泛的跨学科合作为减少癌症的痛苦和死亡率提供了新的机会。 该联盟的教师被组织成13个生产性的研究计划，重点是公共卫生（生物统计学、流行病学、癌症预防）、临床（移植生物学和临床移植）和基础科学（基础科学，干/祖细胞生物学，基因组不稳定性和突变），以及高度跨学科的计划（妇女癌症;前列腺癌; GI癌症病因学，预防和早期检测;癌症成像;以及免疫学和疫苗开发）。 在下一个资助期内，该联盟将寻求：（1）加强其临床研究计划和基础设施，以加快诊断和治疗的发展;（2）加强其在遗传/基因组学方面的存在;（3）加强其在计算生物学方面的存在;（4）继续致力于早期癌症检测，包括蛋白质生物标志物发现和分子诊断;（5）加强在传染病和病毒学研究方面的领导地位，并制定一个以传染源和癌症为重点的计划;（6）继续在基础生物学的广泛领域招募有前途的实验室科学家;（7）继续鼓励和支持相关计划关注老龄化。

DESCRIPTION (provided by applicant): The Fred Hutchinson/University of Washington Cancer Consortium (Consortium), formed in 2002, is a partnership of: Fred Hutchinson Cancer Research Center, an NCI-designated Comprehensive Cancer Center since 1976 and a CCSG grant recipient since 1973; the University of Washington; and Children's Hospital and Regional Medical Center. The Consortium brings together more than 400 faculty with research interests in basic, clinical and public health sciences related to cancer, with total NCI funding of $73 million (direct costs). The goal of the Consortium is the elimination of cancer through more effective prevention, diagnostics, and treatment, deriving from fundamental insights into the biology of the disease. The extensive interdisciplinary collaboration between the three institutions in the cancer research disciplines of basic, clinical, and public health sciences affords new opportunities to reduce suffering and mortality from cancer. The Consortium faculty are organized into 13 productive research programs with emphasis in the Public Health (Biostatistics, Epidemiology, Cancer Prevention), Clinical (Transplantation Biology and Clinical Transplantation), and Fundamental sciences (Basic Sciences, Stem/Progenitor Cell Biology, Genome Instability & Mutagenesis), as well as programs that are highly cross-disciplinary (Women's Cancer; Prostate Cancer; Gl Cancer Etiology, Prevention, & Early Detection; Cancer Imaging; and Immunology & Vaccine Development). During the next grant period the Consortium will seek to: (1) Strengthen its clinical research programs and infrastructure to permit more rapid development of diagnostics and therapeutics; (2) Strengthen its presence in genetic/genomics; (3) Strengthen its presence in computational biology; (4) Continue its commitment to early cancer detection, including protein biomarker discovery and molecular diagnostics; (5) Build on leadership in research on infectious diseases and virology and develop a program focusing on infectious agents and cancer; (6) Continue to recruit promising laboratory scientists in broad areas of basic biology; and (7) Continue to encourage and support a focus on aging for relevant programs.