The Effects of Minnesota State and Local Programs on Young Adult Tobacco Use

描述（由申请人提供）：本提案是对CA86191基金续期请求的重新提交，该基金最初于2000年由NCI在一个特殊的RFA“州和社区烟草控制干预研究”下资助，然后于2004年续期。明尼苏达州青少年社区队列（MACC）研究是一项基于人群的队列研究，招募了4,825名12至16岁的青少年（N= 4220来自明尼苏达州，N=605来自比较州）。自2000-2001年以来，每六个月对参与者进行一次电话调查，了解他们的烟草使用情况和相关态度和信念，共15轮调查了14个数点（MACC 1包括第1-6轮，MACC 2包括第8-15轮，由于资金缺口而省略了第7轮）。获得了额外的资金，用于继续收集额外一轮的数据，以具体评估明尼苏达州全州无烟空气法对青少年吸烟的短期影响（MACC 3，第17轮；2008年10月至2009年3月）。第17轮的参与者年龄在18到25岁之间。我们已申请ARRA行政补充资金进行第19轮（2009年10月至2010年3月）。MACC队列具有许多独特而重要的特征。与许多针对年轻人的研究不同的是，这个队列包括了没有上大学的年轻人和正在上大学的年轻人。国家和州一级的数据显示，烟草使用在没有上大学的年轻人中更为普遍，需要研究评估烟草预防计划和政策如何影响这一群体。在MACC队列中收集了关于青少年吸烟态度和行为的详细和频繁的数据。使用复杂的数据分析技术，我们可以提供比许多以前的研究（数据收集点之间的间隔较长）更详细的关于青春期和青年期烟草使用的开始和进展的信息。MACC队列的大规模使我们能够检查烟草预防计划和政策对年轻人亚组的不同影响，更精确地表征烟草进展模式，识别不常见的进展模式，并区分年龄，队列和时期的影响。最后，我们将烟草使用的个人数据与烟草政策、学校课程、媒体接触和社区长期以来的其他环境特征联系起来。使用这些关联数据并扩大这一队列将使我们能够检查青少年接触各种计划和政策对青少年烟草使用的长期影响。我们还能够评估年轻人接触新项目和政策（例如，明尼苏达州的无烟空气法）对吸烟行为和态度的影响。我们建议在2010-2011年至2012-2013年期间对MACC队列进行额外的三个年度观察（第21、23和25轮；MACC 4）。我们计划增加有关酒精使用和酒精政策影响的措施。利用这些数据，我们将能够检查烟草和酒精使用之间复杂的相互作用以及烟草和酒精政策对年轻人的交叉影响。

DESCRIPTION (provided by applicant): This proposal is a resubmission of a request for renewal of the grant CA86191, first funded by NCI in 2000 under a special RFA "Research in State and Community Tobacco Control Interventions", and then renewed in 2004. The Minnesota Adolescent Community Cohort (MACC) Study is a population-based cohort study that enrolled 4,825 youth (N=4,220 from Minnesota and N=605 from comparison states) aged 12 to 16. Participants were surveyed by telephone every six months since 2000-2001 about their tobacco use and related attitudes and beliefs, resulting in 14 data points over 15 rounds (MACC 1 includes Rounds 1-6, MACC 2 includes Rounds 8-15, Round 7 omitted due to funding gap). Additional funding was obtained to continue data collection for one additional round to specifically assess the short-term effect of Minnesota's statewide smoke-free air law on young adult smoking (MACC 3, Round 17; October 2008-March 2009). During Round 17 participants were age 18 to 25. We have requested ARRA administrative supplement funding to conduct Round 19 (October 2009-March 2010). The MACC cohort has a number of unique and important features. Unlike many studies of young adults, this cohort includes young adults who are not attending college as well as those who are attending college. National and state-level data show that tobacco use is more prevalent among young adults who are not attending college and studies are needed to assess how tobacco prevention programs and policies may affect this group. Detailed and frequent data have been collected on the MACC cohort regarding smoking attitudes and behaviors during adolescence. Using sophisticated data analytic techniques, we can provide more detailed information about the initiation and progression of tobacco use during adolescence and young adulthood than many previous studies (that have had lengthier intervals between data collection points). The large size of the MACC cohort enables us to examine differential effects of tobacco prevention programs and policies on subgroups of young adults, characterize patterns of tobacco progression with greater precision, identify less common patterns of progression, and distinguish age, cohort, and period effects. Finally, we have linked individual data on tobacco use to tobacco policies, school curricula, media exposure and other environmental characteristics of their communities over time. Using these linked data and extending this cohort will enable us to examine the long-term effects of adolescent exposure to various programs and policies on young adult tobacco use. We are also able to assess the effects of young adult exposure to new programs and policies (e.g., Minnesota's smoke-free air law) on smoking behavior and attitudes. We propose to follow the MACC cohort for an additional three annual observations from 2010-2011 to 2012-2013 (Rounds 21, 23, and 25; MACC 4). We plan to add measures concerning alcohol use and exposure to alcohol policies. Using these data, we will be able to examine the complex interplay between tobacco and alcohol use and the crossover effects of tobacco and alcohol policies in young adults. PUBLIC HEALTH RELEVANCE: Continuing the MACC Study will allow us to examine the effects of adolescent exposure to tobacco programs and policies on young adult tobacco use. By collecting additional information about alcohol use and alcohol policies, we will be able to study the complex interplay between tobacco and alcohol use and the crossover effects of tobacco and alcohol policies in young adults.