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中文摘要
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申请者描述(申请人提供):本申请的目的是为生物医学工程学会(BMES)和生物医学物理调节学会(SPRBM)细胞和分子生物工程(CMBE)联合会议(第29届SPRBM年度科学会议)寻求资金。2011年联合会议的具体主题将是:分子成像和机械转导。BME和SPRBM都认识到了细胞和分子生物工程的重要性。2008年,BMES成立了一份新的社会期刊《细胞和分子生物工程》。现在,关于CBME的首届BMES-SPRBM联合会议是生物医学工程这一前景广阔的子领域新焦点的开始,也是这一令人兴奋的领域和新的CMBE杂志亟需的论坛。这个R13应用程序的具体目标有两个。第一个是为受邀的主旨演讲者、初级研究人员、博士后研究员和研究生提供资金支持,这些人提交的论文已根据科学价值被选为讲台发言。会议将为发展长期的跨学科互动提供平台,并使生物工程、生物学和医学的研究人员在分子成像和机械转导的交汇处接触到最新的想法和机会。R13申请的第二个目标是促进CMBE这一激动人心的子领域的出现和发展。本次会议的具体目标是:具体目标1:描述分子成像和机械生物学的现状。来自分子/细胞/组织生物力学领域对分子成像和力学转导领域感兴趣和应用的领导人将概述分子成像的概念,并回顾机械生物学的现状,以及它们在分子/细胞/组织/功能和组织/器官再生方面的研究。具体目标#2:对细胞和分子生物工程的新兴领域进行头脑风暴,重点是分子成像和机械转导。制定一份关于细胞和分子生物工程领域的白皮书,并向BME和SPRBM学会以及广泛的CMBE社区提供细胞和分子生物工程领域的指导方针和蓝图。白皮书将作为这次联合会议的成果发表在CMBE上。 公共卫生相关性:新兴的细胞和分子生物工程子领域是新千年生物医学的一个重要领域。这项申请的目标是为首届生物医学工程学会(BMES)和生物与医学物理调节学会(SPRBM)细胞和分子生物工程(CMBE)联合会议寻求资金。会议将促进CMBE这一激动人心的子领域的出现和发展。
英文摘要
DESCRIPTION (provided by applicant): The goal of this application is to seek funding for the inaugural joint Biomedical Engineering Society (BMES) and the Society for Physical Regulation in Biology and Medicine (SPRBM) Conference on Cellular and Molecular Bioengineering (CMBE) (29th SPRBM Annual Scientific Conference). The specific theme of 2011 joint conference will be: Molecular Imaging and Mechanotransduction. Both the BMES and the SPRBM realized the importance of Cellular and Molecular Bioengineering. In 2008, the BMES formed a new society journal, Cellular and Molecular Bioengineering. Now, the inaugural joint BMES-SPRBM Conference on CBME is the beginning of a new focus of the promising subfield in biomedical engineering and much needed forum for this exciting field and the new CMBE journal. The specific objectives of this R13 application are two-fold. The first is to provide funding support to invited Keynote speakers, junior researchers, postdoctoral fellows, and graduate students whose submitted papers have been selected for podium presentation on the basis of scientific merits. The meeting will provide a platform for the development of long-term interdisciplinary interactions, and expose researchers in bioengineering, biology, and medicine to the latest ideas and opportunities at the confluence of molecular imaging and mechanotransduction. The second objective of this R13 application is to foster the emergence and growth of the exciting sub-filed of CMBE. The specific aims of this meeting are: Specific Aim #1: Delineate the current status of molecular imaging and mechanobiology. Leaders from the molecular/cellular/tissue biomechanics with interests and applications in molecular imaging and mechanotransduction fields will give an overview of molecular imaging concepts and review the current state of mechanobiology, as well as their research in molecular/cellular/tissue/ functions and tissue/organ regeneration. Specific Aim #2: Brainstorm the emerging field of cellular and molecular bioengineering with a focus on molecular imaging and mechanotransduction. Formulate a whitepaper regarding the field of cellular and molecular bioengineering and provide guidelines and blueprints for the cellular and molecular bioengineering field to BMES and SPRBM societies as well as the broad CMBE communities. The whitepaper will be published in the CMBE as the outcome of this joint conference. PUBLIC HEALTH RELEVANCE: The emerging Cellular and Molecular Bioengineering subfield is an important biomedical area in the new millennium. The goal of this application is to seek funding for the inaugural joint Biomedical Engineering Society (BMES) and the Society for Physical Regulation in Biology and Medicine (SPRBM) Conference on Cellular and Molecular Bioengineering (CMBE). The conference will foster the emergence and growth of the exciting sub-filed of CMBE.
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会议论文
STUDY OF MOLECULAR DYNAMICS IN LEUKOCYTE-ASSISTED MELANOMA EXTRAVASATION
Multiscale modeling of leukocyte-tumor cell adhesion to endothelium in shear flow
STUDY OF MOLECULAR DYNAMICS IN LEUKOCYTE-ASSISTED MELANOMA EXTRAVASATION
Multiscale modeling of leukocyte-tumor cell adhesion to endothelium in shear flow
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