SINGLE CRYSTAL XAS OF CUSF

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 初步的结晶学测量表明，在铜外排蛋白CusF中有一个前所未有的金属结合部位，具有新的有机金属结构。然而，晶体的分辨率适中，更重要的是，晶体在金属附近无序，只有部分金属位占据。溶液和单晶XAS的组合将被用来为这个明显史无前例的金属遗址提供详细的局部结构信息。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Initial crystallographic measurements suggest an unprecedented metal binding site in the Cu efflux protein CusF, with a novel organometallic structure. However, the crystal has modest resolution and more importantly is disordered near the metal, with only partial metal-site occupancy. A combination of solution and single crystal XAS will be used to provide detailed local structural information for the apparently unprecedented metal site.