A STUDY TO ASSESS THE CARDIOVASCULAR, COGNITIVE AND SUBJECTIVE EFFECTS OF ATOMOX

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 检查托莫西汀对MA产生的心血管和主观效应的影响。 我们将评价托莫西汀（0和80 mg，PO）和MA（脱氧麻黄碱）剂量（0和30 mg，IV）。将通过测量MA的心血管效应和确定托莫西汀和安慰剂治疗期间不良反应的发生率来表征托莫西汀在MA使用者中的安全性。 将使用视觉模拟量表评估主观效应。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. To examine the effects of atomoxetine on the cardiovascular and subjective effects produced by MA. We will evaluate atomoxetine (0 and 80 mg, PO) and MA (desoxyn) doses (0 and 30 mg, IV). The safety of using atomoxetine in MA users will be characterized by measuring the cardiovascular effects of MA and by determining the occurrence of adverse reactions during treatment with atomoxetine and placebo. Subjective effects will be assessed using visual-analogue scales.