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Computational modeling of human metabolism, body weight and composition

Computational modeling of human metabolism, body weight and composition
人体新陈代谢、体重和成分的计算模型
批准号：
8148671
负责人：
KEVIN HALL
金额：
$35.61万
依托单位：
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8148671
关键词：
Body WeightComputer SimulationHumanMetabolism

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中文摘要
翻译
我们继续开发人体宏量营养素代谢的数学模型，并利用各种已发表的数据进行了几项验证研究，这些数据涉及饮食宏量营养素过量、不足和等热量变化的代谢反应。该模型已与美国国立卫生研究院临床研究人员合作，作为临床研究工具，帮助设计前瞻性研究以及计划和跟踪临床体重管理项目。我们的模型被应用于各种各样的问题，从计算人类体重变化与食物摄入量之间的关系到计算美国食物浪费的逐步增加。
英文摘要
We continue to develop mathematical models of human macronutrient metabolism and have conducted several validation studies using a variety of published data on the metabolic responses to overfeeding, underfeeding, and isocaloric changes in dietary macronutrients. The model has been deployed as a clinical research tool in collaboration with NIH clinical investigators to help design prospective studies as well as plan and track clinical weight management programs. Our models are being applied to a variety of problems, from calculating the relationship between human weight change and food intake to calculating the progressive increase of US food waste.
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会议论文
Interactions of diet, exercise, metabolism, and weight change in humans
Computational modeling of human metabolism, body weight and composition
Regulation of rodent energy metabolism, body weight and composition
Regulation of rodent energy metabolism, body weight and composition
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