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Clinical protocols for the treatment of GI cancer

Clinical protocols for the treatment of GI cancer
胃肠道癌症治疗的临床方案
批准号：
8175365
负责人：
Tim Greten
金额：
$3.44万
依托单位：
DIVISION OF BASIC SCIENCES - NCI
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8175365
关键词：
Blood VesselsCessation of lifeClinical ProtocolsColon CarcinomaGastrointestinal NeoplasmsHepatobiliaryImmuneImmune responseLiverMalignant NeoplasmsMalignant neoplasm of gastrointestinal tractMalignant neoplasm of pancreasMolecular TargetOperative Surgical ProceduresRadiation therapyTestingUnited Stateschemotherapyinteresttreatment effecttumor

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中文摘要
翻译
胃肠道癌是美国肿瘤相关死亡的主要原因之一。目前的治疗选择仅限于手术、化疗、放疗和分子靶向治疗，迫切需要新的治疗选择。血管靶向剂代表了一种有趣的治疗选择，不仅因为许多GI肿瘤高度血管化，而且因为它们已经被证明对不同类型的GI癌症（包括肝癌和结肠癌）有效。因此，我们计划启动临床方案，旨在测试用于治疗不同类型GI癌症的新血管靶向方法。
英文摘要
Gastrointestinal cancer represent one of the major reasons for tumor related death in the United States. Current treatment options are limited to surgery, chemotherapy, radiation therapy and molecular targeted therapy and new treatment options are urgently needed. Vascular targeting agents represent an interesting treatment option not only because a number of GI tumors are highly vascularized, but also because they have already been shown to be effective in different types of GI cancer including liver and colon cancer. Therefore we plan to initiate clinical protocols aiming testing new vascular targeting approaches for the treatment of different types of GI cancer.
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