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Study the chromatin binding proteins in embryonic stem cells

Study the chromatin binding proteins in embryonic stem cells
研究胚胎干细胞中的染色质结合蛋白
批准号:
8157734
负责人:
Jing Huang
金额:
$39.77万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
干细胞治疗具有巨大的临床应用潜力。胚胎干细胞是产生各种不同类型成体干细胞的无限来源。然而,胚胎干细胞向成体干细胞分化过程中的事件尚不清楚,尽管人们认为表观遗传事件对这一过程至关重要。我们计划在胚胎干细胞中研究染色质结合蛋白。染色质结合蛋白是调控表观遗传事件的关键蛋白。因此,本项目将为胚胎干细胞的分化过程提供分子视角,促进胚胎干细胞的临床应用。
英文摘要
Stem cell therapy have great potentials in clinical application. ES cells represent an unlimited source to generate all different types of adult stem cells. However, the events during the differentiation of ES cells into adult stem cells are unclear, although it is thought that epigenetic events are critical for this process. We plan to study the chromatin binding proteins in ES cells. Chromatin binding proteins are proteins which are critical for regulating the epigenetic events. Therefore, this project will provide molecular insights into the differentiation process of ES cells and faciliate the clinical utilization of ES cells.
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CK22-008 Characterizing dynamics of pandemic and preparing for speedy and accurate response
  • 批准号:
    10696114
  • 项目类别:
  • 资助金额:
    $5.82万
  • 财政年份:
    2022
  • 负责人:
    Jing Huang
  • 依托单位:
Characterizing dynamics of pandemic and preparing for speedy and accurate response
  • 批准号:
    10617938
  • 项目类别:
  • 资助金额:
    $29.05万
  • 财政年份:
    2022
  • 负责人:
    Jing Huang
  • 依托单位:
Characterizing Disease Trajectory for Improving Treatment in Pediatric Crohn's Disease
  • 批准号:
    10414884
  • 项目类别:
  • 资助金额:
    $61.68万
  • 财政年份:
    2019
  • 负责人:
    Jing Huang
  • 依托单位:
Characterizing Disease Trajectory for Improving Treatment in Pediatric Crohn's Disease
  • 批准号:
    10641954
  • 项目类别:
  • 资助金额:
    $61.68万
  • 财政年份:
    2019
  • 负责人:
    Jing Huang
  • 依托单位:
海外基金