Bioengineering Cardiovascular Training Grant

 描述(由申请人提供)：该计划的目的是为致力于心血管研究事业的个人提供生物工程培训。心血管疾病是美国主要的死亡原因，这一领域的健康进步需要培养具有不同背景和优势的杰出科学家，为心血管疾病的研究、诊断和治疗提供新的创新方法。近40年来，华盛顿大学和生物工程系一直是心血管研究和技术开发的领先者。工程学院和医学院的多个系的教员在这一领域有很强的合作计划。该计划将通过培训基础科学和转化研究方面的专业人员使公众受益，这些研究整合了工程、数学、化学、生理学、物理学和计算技能，以促进基础发现和开发新技术。还提供了技术商业化以及如何将研究和设备推向临床应用方面的培训。我们的计划侧重于对博士前学生进行协作、跨学科的培训，重点是将诊断和治疗中的新生物工程技术应用于心血管病理的研究和治疗。这将改善心力衰竭患者的早期发现，延长患者的生活质量。我们认为，翻译研究的成功需要学术界和工业界训练有素的科学家，以及那些能够成功地将研究从大学转化为商业化和临床的科学家。我们计划的使命是提供培训，以实现这些目标中的每一个。该计划包括1)选定导师的实验室研究，2)我们受训人员独有的教学组件，以及额外的翻译和商业化培训机会，以及3)我们计划独有的临床指导。学员还被要求参加以简历研究为重点的系列研讨会，并与仅限于学员的演讲者举行特别相关会议，以及由医学院赞助的生物医学研究诚信暑期计划的讲座和讨论小组。受训者的选择是基于强大的量化和工程背景、教师导师的培训环境、研究是否适合我们的计划重点以及创新、合作和翻译研究的潜力。受训者出席年度研讨会，出席全国会议，有一个月刊俱乐部，并撰写年度进展报告。他们还必须在为期两年的培训期结束时申请研究金，以获得后续资金，并建立在获得研究支助方面的成功竞争记录。

 DESCRIPTION (provided by applicant): The purpose of this program is to provide Bioengineering training for individuals committed to careers in cardiovascular research. Cardiovascular (CV) diseases are the leading cause of mortality in the United States and health progress in this area will require training outstanding scientists with a variety of backgrounds and strengths that can provide new and innovative approaches to the study, diagnosis and treatment of CV disease. The University of Washington and Department of Bioengineering have been leaders in cardiovascular research and technology development for almost 40 years. Faculty in multiple departments in the College of Engineering and School of Medicine have strong collaborative programs in this area. The program will benefit the public by training professionals in basic science and translational research that integrates engineering, mathematics, chemistry, physiology, physics and computational skills to promote fundamental discoveries and develop new technologies. Training is also provided in commercialization of technologies and how to move research and devices towards clinical application. Our program focuses on collaborative, interdisciplinary training of pre-doctoral students with an emphasis on applying new bioengineering technologies in diagnostics and therapeutics to the study and treatment of CV pathologies. This will improve early detection and extend the quality of life for patients suffering from heart failure. We believe that the success of translational research requires highly trained scientists in both academia and industry, as well as those who can successfully transition research from universities to commercialization and the clinic. The mission of our program is to provide training that can accomplish each of these goals. The program involves 1) research in the laboratory of a chosen mentor, 2) didactic components that are unique to our trainees plus additional opportunities for training in translational and commercialization, and 3) clinical preceptorships that are unique to our program. Trainees are also required to attend a seminar series focused on CV research, with special associated sessions with speakers that are limited to trainees, as well as lectures and discussion groups in the Biomedical Research Integrity summer program, sponsored by the School of Medicine. Trainees are selected based on strong quantitative and engineering backgrounds, training environment of faculty mentors, appropriateness of the research to our programmatic focus and the potential for innovative, collaborative and translational research. Trainees present at a yearly symposium, present at national meetings, have a monthly journal club and write a yearly progress report. They are also required to apply for fellowships at the end of the two-year training period for follow-on funding and to establish a record of successful competition in gaining research support.