Preclinical evaluation of F-18 fluoroethyltriazolyl PEGstilbenes as potential PET imaging agents for Alzheimers disease

阿尔茨海默病（AD）是最常见的痴呆症形式，由于人口老龄化，它正成为卫生系统日益增加的负担。淀粉样斑块被认为是阿尔茨海默病的标志，在体内检测它们的技术将是一个突破，不仅对阿尔茨海默病的诊断，而且对阿尔茨海默病药物的开发。核医学可以对组织功能进行无创成像。本项目旨在开发新的显像剂以提高对AD的诊断。

Alzheimer's disease (AD) is the most common form of dementia and is becoming am ever increasing burden to the health system due to the aging of our population. Amyloid plaques are considered the hallmark of AD and a technique for their detection in vivo would be a breakthrough, not only for the diagnosis of AD but also for the development of drugs against AD. Nuclear medicine can image tissue function non-invasively. This project aims to develop new imaging agents to improve diagnosis of AD.