课题基金 / 基金详情

Blocking IL-6 trans-signaling: a therapeutic strategy to prevent metabolic disease

Blocking IL-6 trans-signaling: a therapeutic strategy to prevent metabolic disease
阻断 IL-6 反式信号传导:预防代谢疾病的治疗策略
批准号:
nhmrc : 1041760
负责人:
Prof Mark Febbraio
金额:
$36.05万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2015-12-31

项目摘要

项目成果

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中文摘要
翻译
众所周知,阻断特异性免疫细胞即巨噬细胞向肥胖患者脂肪组织的募集将改善其代谢健康。然而,迄今为止,一种可行的药物仍然难以捉摸。我们已经开发了一种叫做sgp130Fc的药物。该项目将在临床前测试该药物的有效性。
英文摘要
It is well known that blocking the recruitment of specific immune cells namely macrophages to adipose tissue of obese patients will improve their metabolic health. However, to date, a viable drug to do this has remained elusive. We have developed such a drug called sgp130Fc. This project will test the effectiveness of this drug in a pre-clinical setting.
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Mapping and defining inter-organ cross talk during exercise
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国内基金
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