CAMERA: Combination antibiotic treatment for Methicillin Resistant Staphylococcus Aureus Bacteraemia - a Randomised Controlled Trial

金黄色葡萄球菌对最有用的抗生素类：β-内酰胺类抗生素具有耐药性。它比抗生素敏感的菌株更难治疗。耐甲氧西林金黄色葡萄球菌的标准治疗方法是万古霉素，但失败率很高。虽然MRSA对β-内酰胺类抗生素具有耐药性，但实验室研究表明，当它们联合使用时，可以增强万古霉素的杀菌作用。CAMERA2是一项随机对照试验，比较了单用万古霉素和联合治疗(万古霉素加氟氯西林)治疗成人MRSA血流感染的疗效

MRSA (golden staph) is resistant to the most useful class of antibiotics: beta-lactams. It is more difficult to treat than antibiotic-sensitive strains. Standard treatment for MRSA is vancomycin but it has high failure rates. Although MRSA is resistant to beta-lactams, lab studies show that they enhance vancomycin’s bacterial killing when used together. CAMERA2 is an RCT comparing vancomycin alone to combination therapy (vancomycin plus flucloxacillin) for adults with MRSA blood stream infection