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CAMERA: Combination antibiotic treatment for Methicillin Resistant Staphylococcus Aureus Bacteraemia - a Randomised Controlled Trial

CAMERA: Combination antibiotic treatment for Methicillin Resistant Staphylococcus Aureus Bacteraemia - a Randomised Controlled Trial
CAMERA:抗生素联合治疗耐甲氧西林金黄色葡萄球菌菌血症 - 一项随机对照试验
批准号:
nhmrc : 1078930
负责人:
A/Pr Joshua Davis
金额:
$77.5万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2019-12-31

项目摘要

项目成果

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中文摘要
翻译
MRSA(金黄色葡萄球菌)对最有用的一类抗生素:β-内酰胺类抗生素具有耐药性。它比抗生素敏感菌株更难治疗。MRSA的标准治疗是万古霉素,但失败率很高。虽然MRSA对β-内酰胺类抗生素有耐药性,但实验室研究表明,当它们一起使用时,它们可以增强万古霉素的杀菌作用。CAMERA 2是一项比较万古霉素单药与联合治疗(万古霉素+氟氯西林)治疗MRSA血流感染成人的RCT
英文摘要
MRSA (golden staph) is resistant to the most useful class of antibiotics: beta-lactams. It is more difficult to treat than antibiotic-sensitive strains. Standard treatment for MRSA is vancomycin but it has high failure rates. Although MRSA is resistant to beta-lactams, lab studies show that they enhance vancomycin’s bacterial killing when used together. CAMERA2 is an RCT comparing vancomycin alone to combination therapy (vancomycin plus flucloxacillin) for adults with MRSA blood stream infection
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Strengthening the evidence base for the management of common severe infectious diseases
  • 批准号:
    nhmrc : GNT1160331
  • 项目类别:
    Career Development Fellowships
  • 资助金额:
    $29.0万
  • 财政年份:
    2019
  • 负责人:
    A/Pr Joshua Davis
  • 依托单位:
Bacterial and Host Drivers of Fulminant Community-acquired Acinetobacter baumannii Infection
  • 批准号:
    nhmrc : 1144294
  • 项目类别:
    Project Grants
  • 资助金额:
    $49.31万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Joshua Davis
  • 依托单位:
Bacterial and Host Drivers of Fulminant Community-acquired Acinetobacter baumannii Infection
  • 批准号:
    nhmrc : GNT1144294
  • 项目类别:
    Project Grants
  • 资助金额:
    $72.93万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Joshua Davis
  • 依托单位:
Addressing important evidence gaps in the management of severe infectious diseases
  • 批准号:
    nhmrc : 1083105
  • 项目类别:
    Career Development Fellowships
  • 资助金额:
    $17.13万
  • 财政年份:
    2015
  • 负责人:
    A/Pr Joshua Davis
  • 依托单位:
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