Regulation of the haemostatic activity of plasma von Willebrand factor
Regulation of the haemostatic activity of plasma von Willebrand factor
批准号:
nhmrc : GNT1110219
负责人:
Prof Philip Hogg
金额:
$85.2万
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 --
中文摘要
我们的基因编码执行生命任务的蛋白质。大多数蛋白质在被制造来控制它们如何、何时和在哪里发挥作用后,都会进行化学修饰。霍格教授发现了一种新的蛋白质化学修饰,这对健康和疾病都很重要。他将利用这一发现开发心脏病发作和中风的新诊断和治疗方法。霍格教授是为数不多的将实验室开发的新诊断和治疗方法用于患者评估的澳大利亚人之一。
英文摘要
Our genes encode proteins that perform the tasks of life. Most proteins are chemically modified after they are made to control how, when, and where they function. Prof Hogg discovered a new chemical modification of proteins that is important in health and disease. He will apply this discovery to develop new diagnostics and therapies for heart attacks and stroke. Prof Hogg is one of the few Australians to take new diagnostics and therapies developed in the lab to evaluation in patients.
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会议论文
Essential role of ERp5 in thrombosis
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批准号:nhmrc : 1143400
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项目类别:Project Grants
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资助金额:$30.32万
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财政年份:2018
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负责人:Prof Philip Hogg
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依托单位:
Redefining the pro-thrombotic mechanism of von Willebrand factor
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批准号:nhmrc : 1143398
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项目类别:Project Grants
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资助金额:$50.71万
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财政年份:2018
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负责人:Prof Philip Hogg
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依托单位:
Redefining the pro-thrombotic mechanism of von Willebrand factor
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批准号:nhmrc : GNT1143398
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项目类别:Project Grants
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资助金额:$75.0万
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财政年份:2018
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负责人:Prof Philip Hogg
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依托单位:
Regulation of the haemostatic activity of plasma von Willebrand factor
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批准号:nhmrc : 1110219
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项目类别:Research Fellowships
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资助金额:$58.74万
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财政年份:2016
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负责人:Prof Philip Hogg
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依托单位:
Mechanism of action and targeting of RAGE in inflammation
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批准号:nhmrc : 1043095
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项目类别:Project Grants
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资助金额:$25.77万
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财政年份:2013
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负责人:Prof Philip Hogg
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依托单位:
Mechanism of action and targeting of hexokinase II in glioblastoma
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批准号:nhmrc : 1043094
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项目类别:Project Grants
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资助金额:$42.92万
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财政年份:2013
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负责人:Prof Philip Hogg
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依托单位:
The Ghost in the Machine: understanding how haemostasis is regulated by allosteric disulphide bonds
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批准号:nhmrc : 1002645
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项目类别:Research Fellowships
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资助金额:$59.88万
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财政年份:2011
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负责人:Prof Philip Hogg
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依托单位:
Research Fellowship - Grant ID:401103
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批准号:nhmrc : 401103
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项目类别:NHMRC Research Fellowships
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资助金额:$55.09万
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财政年份:2006
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负责人:Prof Philip Hogg
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依托单位:
Activation of Tissue Factor by a Disulphide-Bond Switch
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批准号:DP0559626
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项目类别:Discovery Projects
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资助金额:$29.15万
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财政年份:2005
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负责人:Prof Philip Hogg
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依托单位:
Vascular biology in thrombosis - Chesterman Program
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批准号:nhmrc : 157204
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项目类别:NHMRC Research Fellowships
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资助金额:$40.13万
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财政年份:2001
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负责人:Prof Philip Hogg
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依托单位:
海外基金