Inert atmosphere glovebox for synthetic inorganic, organometallic chemistry at ryerson

提议的设备是惰性气氛双手套箱，用于瑞尔森大学进行的合成无机，有机和聚合物化学的各种应用。手套箱的惰性气氛允许制备，储存和安全处理少量的水分和空气敏感化合物。通过在干燥柱上的惰性气氛（氮气或氩气）的连续再循环，水分和空气水平保持在< 1ppm。通过小型和大型港口门，方便了热敏性或湿气敏感材料的储存和转移。反应、称重操作、样品制备和敏感材料的晶体生长在手套箱中安全、方便地进行。低温冰箱（-35℃）提供了在手套箱中存储热敏反应材料的额外优势，或者作为重新结晶回收空气和湿气敏感材料的合适位置。正确使用手套箱可以提高合成产量，延长敏感材料的保质期和储存时间，以及更安全的工作条件。在这个RTI上，参与者将实现更高的生产率和更大程度的安全期望。Daniel Foucher将使用这个手套箱来制备空气和水分敏感锡化合物，用于制备用于喷墨印刷电路的聚合物。Rob gosage将使用手套箱来制备和再结晶对空气和水分敏感的过渡金属复合物，作为催化剂和乳腺癌治疗的应用。Russell Viirre将使用该设备开发用于合成药物化合物和分子传感器的新反应。

The proposed equipment is an inert atmosphere double glovebox required for a variety of applications in the synthetic inorganic, organic and polymer chemistries carried out at Ryerson University.  The inert atmosphere of the glovebox allows for the preparation, storage and safe handling of small to moderate quantities of moisture and air sensitive compounds. Moisture and air levels are maintained at < 1 ppm by the continuous recirculation of the inert atmosphere (Nitrogen or Argon) over drying columns. Storage and transfer of pyrophoric or moisture sensitive materials is facilitated by ready access through small and large port doors.  Reactions, weighing operations, sample preparation, and crystal growth of sensitive materials are safely and readily carried out in the glovebox. The low temperature refrigerator (-35 oC) provides an additional advantage of storing heat sensitive reactive materials in the glove box, or as a suitable location to recrystallize recovered air and moisture sensitive materials. Proper use of the glovebox can lead to higher synthetic yields, longer shelf life and storage of sensitive materials, and safer working conditions. The higher productivity and greater degree of safety expected with the glovebox would be realized by the participants on this RTI.  Daniel Foucher will use this glovebox to prepare air and moisture sensitive tin compounds in the preparation of polymers for applications in inkjet printable circuitry. Rob Gossage will use the glovebox to prepare and recrystalize air and moisture sensitive transition metal complexes with applications as catalysts and breast cancer therapies. Russell Viirre will use this equipment in the development of new reactions for the synthesis of medicinal compounds and molecular sensors.