Regulation of RNA processing in the mitochondrial disease MELAS

线粒体是微小的、产生能量的机器，存在于所有人类细胞中。线粒体包含一小组基因，这些基因必须正常工作，才能产生我们身体健康所需的能量。线粒体基因表达的缺陷会导致衰弱的疾病，目前还没有治愈的方法。我们已经开发了一套新的技术，这些技术将被应用于了解这些突变是如何导致疾病的，并为可能的治疗提供见解。

Mitochondria are microscopic, energy producing machines that are found in all human cells. Mitochondria contain a small set of genes that must work properly to make the energy our bodies require for health. Defects in the expression of mitochondrial genes cause debilitating diseases for which there are currently no cures. We have developed a new set of technologies that will be applied to understand how these mutations cause disease and provide insights into possible treatments.