The role of metals in healthy brain aging: identification of novel compounds to prevent age-related cognitive decline
The role of metals in healthy brain aging: identification of novel compounds to prevent age-related cognitive decline
批准号:
nhmrc : 1027379
负责人:
A/Pr Paul Adlard
金额:
$52.66万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2014-12-31
中文摘要
这项资助将探索正常学习和记忆的基本机制。具体地说,我们正在关注金属水平的调节如何随着年龄的增长而发生,以及这可能如何导致或至少有助于与年龄相关的认知障碍。我们还在研究一种治疗认知功能障碍的新型治疗化合物。这项工作将对正常和病理性衰老都有影响。
英文摘要
This grant will explore the basic mechanisms that underlie normal learning and memory. Specifically, we are focussing on how the modulation of metal levels may occur with age, and how this may cause or at least contribute to age-related cognitive impairment. We are also examining a novel therapeutic compound for the treatment of cognitive dysfunction. This work will have implications for both normal and pathological ageing.
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会议论文
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批准号:nhmrc : GNT1141597
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项目类别:Project Grants
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资助金额:$122.98万
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财政年份:2018
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负责人:A/Pr Paul Adlard
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依托单位:
Metal-mediated mechanisms and therapeutic approaches for treating brain injury across age
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项目类别:Project Grants
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负责人:A/Pr Paul Adlard
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依托单位:
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批准号:nhmrc : 1025774
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项目类别:Project Grants
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资助金额:$43.36万
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财政年份:2012
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负责人:A/Pr Paul Adlard
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依托单位:
Modulating beta-amyloid aggregation and toxicity with natural metal-binding proteins
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批准号:nhmrc : 605528
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项目类别:NHMRC Project Grants
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资助金额:$26.62万
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财政年份:2010
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负责人:A/Pr Paul Adlard
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依托单位:
Novel therpeutic approaches for Alzheimers disease
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批准号:nhmrc : 508974
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项目类别:NHMRC Project Grants
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资助金额:$40.32万
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财政年份:2008
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负责人:A/Pr Paul Adlard
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依托单位:
The effect of metals on neurofibrillary tangle formation
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批准号:nhmrc : 509276
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项目类别:NHMRC Project Grants
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资助金额:$22.23万
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财政年份:2008
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负责人:A/Pr Paul Adlard
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依托单位:
Effect of dietary copper on evolution of Alzheimer's disease (AD)-like neuropathological & neurochemical alterations...
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批准号:nhmrc : 400401
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项目类别:Early Career Fellowships
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资助金额:$11.59万
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财政年份:2006
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负责人:A/Pr Paul Adlard
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依托单位:
国内基金
海外基金
Rare Metals(稀有金属(英文版))
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批准号:51224002
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项目类别:专项基金项目
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资助金额:20.0万元
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批准年份:2012
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负责人:钱九红
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依托单位:
红树对重金属的定位累积及耦合微观分析与耐受策略研究
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批准号:30970527
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项目类别:面上项目
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资助金额:35.0万元
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批准年份:2009
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负责人:严重玲
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依托单位: