SARA: Delineating its Association with the Onset and Development of Liver Fibrosis
SARA: Delineating its Association with the Onset and Development of Liver Fibrosis
批准号:
nhmrc : 1100088
负责人:
Dr Daniel Wallace
金额:
$59.57万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2016
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2016-01-01 至 2019-12-31
中文摘要
肝病是社会的一个重大负担,影响着许多正值壮年的人。肝脏瘢痕形成是由酒精、病毒、肥胖和脂肪肝疾病等多种因素引起的损伤的反应。我们发现了一种与肝损伤有关的蛋白质。在这个项目中,我们将进行系统的分析,以了解这种蛋白质在损伤进展中的作用。最终,我们打算开发工具来预防和治疗肝损伤。
英文摘要
Liver disease, a significant burden on society, affects many in the prime of their life. Scarring of the liver is a response to injury due to many factors including alcohol, viruses, obesity, and fatty-liver disease. We have identified a protein associated with liver injury. In this project we will perform a systematic analysis to understand the role of this protein in injury progression. Ultimately we intend to develop tools to prevent and treat liver injury.
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SARA: Delineating its Association with the Onset and Development of Liver Fibrosis
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批准号:nhmrc : GNT1100088
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项目类别:Project Grants
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资助金额:$86.6万
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财政年份:2016
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负责人:Dr Daniel Wallace
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依托单位:
Delineating the Relationship between Iron and Peroxisomal Disorders: The Role of the Peroxisomal Enzyme GNPAT in Iron-Overload Disorders
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批准号:nhmrc : GNT1082224
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项目类别:Project Grants
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资助金额:$67.45万
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财政年份:2015
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负责人:Dr Daniel Wallace
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依托单位:
Delineating the Relationship between Iron and Peroxisomal Disorders: The Role of the Peroxisomal Enzyme GNPAT in Iron-Overload Disorders
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批准号:nhmrc : 1082224
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项目类别:Project Grants
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资助金额:$46.73万
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财政年份:2015
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负责人:Dr Daniel Wallace
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依托单位:
Deciphering Signalling Pathways Regulating Iron Homeostasis
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批准号:nhmrc : 1031325
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项目类别:Project Grants
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资助金额:$27.17万
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财政年份:2012
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负责人:Dr Daniel Wallace
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依托单位:
EXAMINING THE RELATIONSHIP BETWEEN MATRIPTASE-2 AND HEMOJUVELIN, TWO ESSENTIAL REGULATORS OF IRON HOMEOSTASIS
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批准号:nhmrc : 613643
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项目类别:NHMRC Project Grants
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资助金额:$35.58万
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财政年份:2010
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负责人:Dr Daniel Wallace
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依托单位:
Non-HFE haemochromatosis in Australia: natural history and molecular characterisation
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批准号:nhmrc : 552412
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项目类别:NHMRC Project Grants
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资助金额:$12.0万
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财政年份:2009
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负责人:Dr Daniel Wallace
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依托单位:
Hepcidin: The link between cytokines, haemochromatosis and anaemia
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批准号:nhmrc : 443026
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项目类别:Career Development Fellowships
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资助金额:$31.41万
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财政年份:2007
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负责人:Dr Daniel Wallace
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依托单位:
海外基金