Studies of the genetics of spotting in domestic dogs

这项研究将集中在开发DNA测试的狗被发现或打勾。在许多品种中，有几种形式的斑点，并不是所有的都是个人育种者或整个品种所希望的。在其他品种中，只有单一斑点模式的实心或斑点犬，如纽芬兰犬。开发这些品种的DNA测试将需要考虑这些信息。MITF基因最近被证明与狗的某些形式的斑点有关，因此需要更充分地研究。滴答声是一种模式或小色素区域内较大的非色素区域。因此，只有带有白色斑纹的狗才能听到滴答声。我们将研究几个候选基因，以确定它们是否与滴答声有关。

This study will focus on developing DNA tests for dogs that are spotted or ticked. In many breeds there are several forms of spotting and not all are equally desirable by individual breeders or by the breed as a whole. In other breeds there are solid or spotted dogs of only a single pattern of spotting, such as Newfoundlands. Developing DNA testing for these breeds will need to take such information into account. The gene MITF has recently been shown to be associated with some forms of spotting in dogs and so this needs to be studied more fully. Ticking is a pattern or small pigmented areas within larger nonpigmented areas. Hence ticking only shows on dogs with white markings. We will study several candidate genes to determine if they might be associated with ticking.