The structural basis of the interaction of insulin-like peptide 3, a key regulator of fertility, with its receptor.

这种激素，胰岛素样肽3，最近被证明直接作用于男性和女性生殖细胞，导致它们成熟。作为调节生育能力的治疗剂，它有相当大的前景。基于这种多肽的药物可以用来帮助不孕症，而阻止其作用的药物作为男性和女性避孕药具有巨大的潜力。为了实现这些目标，我们的项目旨在了解这种多肽是如何发挥其独特的生物学效应的。

The hormone, insulin-like peptide 3, has recently been shown to act directly on male and female germ cells to cause their maturation. It has considerable promise as a therapeutic agent for the regulation of fertility. Drugs based on the peptide may be used to assist in cases of infertility, and drugs that block its action have great potential as male and female contraceptives. Towards these goals, our project aims to understand how this peptide exerts its unique biological effects.