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Systems immunology of antigen specific T cells: from single-cell to immune protection

Systems immunology of antigen specific T cells: from single-cell to immune protection
抗原特异性T细胞的系统免疫学:从单细胞到免疫保护
批准号:
nhmrc : GNT1128416
负责人:
A/Pr Fabio Luciani
金额:
$47.01万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Career Development Fellowships
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 --

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中文摘要
翻译
T细胞是建立免疫保护的关键,也是疫苗和最近针对感染和某些癌症的免疫疗法的持续研究的对象。它们的动力学是复杂的,许多机制仍然未知,可用于现代疗法。在这里,在一个系统的方法,我将结合单细胞技术,免疫学和计算生物学来确定的因素,决定建立长期记忆细胞利用一组独特的样本。
英文摘要
T cells are key for establishment of immune protection and object of ongoing research in vaccines and more recently immunotherapy against infections and some cancers. Their dynamics are complex and many mechanisms remain unknown that could be exploited for modern therapies. Here, in a systems approach I will combined single cell technologies, immunology and computational biology to identify the factors that determine the establishment of long term memory cells utilising a unique set of samples.
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Systems immunology of antigen specific T cells: from single-cell to immune protection
  • 批准号:
    nhmrc : 1128416
  • 项目类别:
    Career Development Fellowships
  • 资助金额:
    $32.12万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Fabio Luciani
  • 依托单位:
Determining the unique processes that control memory B cell-mediated secondary antibody responses
  • 批准号:
    nhmrc : GNT1124681
  • 项目类别:
    Project Grants
  • 资助金额:
    $85.36万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Fabio Luciani
  • 依托单位:
Determining the unique processes that control memory B cell-mediated secondary antibody responses
  • 批准号:
    nhmrc : 1124681
  • 项目类别:
    Project Grants
  • 资助金额:
    $58.34万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Fabio Luciani
  • 依托单位:
The phenotype of protective cytotoxic T cell responses during viral infections
  • 批准号:
    nhmrc : GNT1121643
  • 项目类别:
    Project Grants
  • 资助金额:
    $84.11万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Fabio Luciani
  • 依托单位:
国内基金
海外基金
Cellular & Molecular Immunology
  • 批准号:
    30824806
  • 项目类别:
    专项基金项目
  • 资助金额:
    20.0万元
  • 批准年份:
    2008
  • 负责人:
    魏海明
  • 依托单位: