Understanding the Immune Response
Understanding the Immune Response
批准号:
nhmrc : GNT1054925
负责人:
Prof David Tarlinton
金额:
$903.06万
依托单位国家:
澳大利亚
项目类别:
Programs
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 --
中文摘要
淋巴细胞在我们的免疫防御中起着至关重要的作用。当淋巴细胞遇到外来入侵者时,如病毒,它们会做出一系列决定,影响所产生的免疫力的强度,类型和寿命。该计划旨在了解淋巴细胞如何在分子水平上做出影响细胞和整个系统水平行为的决定。我们的目标是改进疫苗,了解过敏、狼疮、关节炎和白血病等疾病,以开发新的疗法。
英文摘要
The lymphocyte plays a vital role in our immune defence. When lymphocytes encounter a foreign invader, such as a virus, they make a series of decisions that influence the strength, type, and longevity of the immunity created. This program aims to understand how lymphocytes make decisions at the molecular level that affect cell and whole of system level behaviour. We aim to improve vaccines and understand diseases such as allergy, lupus, arthritis and leukaemia to develop novel therapies.
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会议论文
A Systems Approach to the Adaptive Immune Response
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批准号:nhmrc : 1054925
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项目类别:Program Grants
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资助金额:$631.79万
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财政年份:2014
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负责人:Prof David Tarlinton
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依托单位:
Understanding antibody responses
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批准号:nhmrc : GNT1060675
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项目类别:Research Fellowships
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资助金额:$72.76万
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财政年份:2014
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负责人:Prof David Tarlinton
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依托单位:
The regulation of B cell differentiation and survival in response to antigen challenge
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批准号:nhmrc : 1060675
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项目类别:Research Fellowships
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资助金额:$50.9万
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财政年份:2014
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负责人:Prof David Tarlinton
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依托单位:
The Regulation of Antibody: A Systems Approach
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批准号:nhmrc : 575500
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项目类别:Programs
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资助金额:$540.86万
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财政年份:2009
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负责人:Prof David Tarlinton
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依托单位:
Monoclonal antibodies targeting plasma cells as novel therapeutic agents and diagnostic tools
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批准号:nhmrc : 575575
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项目类别:NHMRC Development Grants
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资助金额:$13.29万
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财政年份:2009
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负责人:Prof David Tarlinton
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 575505
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项目类别:NHMRC Research Fellowships
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资助金额:$46.85万
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财政年份:2009
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负责人:Prof David Tarlinton
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依托单位:
The regulation of antibody: A systems approach
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批准号:nhmrc : 356202
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项目类别:Programs
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资助金额:$291.89万
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财政年份:2005
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负责人:Prof David Tarlinton
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依托单位:
Blimp-1: a master regulator of B-lymphocyte terminal differentiation?
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批准号:nhmrc : 305513
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项目类别:NHMRC Project Grants
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资助金额:$10.29万
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财政年份:2004
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负责人:Prof David Tarlinton
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依托单位:
The quantitative regulation of antibody forming cell differentiation
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批准号:nhmrc : 257526
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项目类别:NHMRC Project Grants
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资助金额:$22.44万
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财政年份:2003
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负责人:Prof David Tarlinton
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依托单位:
Regulating the production of high affinity antibody forming cells during the germinal centre reaction.
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批准号:nhmrc : 215307
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项目类别:NHMRC Project Grants
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资助金额:$25.14万
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财政年份:2002
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负责人:Prof David Tarlinton
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依托单位:
海外基金