Understanding sphingolipid mediators of insulin resistance
Understanding sphingolipid mediators of insulin resistance
批准号:
nhmrc : GNT1126135
负责人:
A/Pr Anthony Don
金额:
$64.34万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 --
中文摘要
鞘脂是一类脂质代谢物,在细胞内具有多种功能。一段时间以来,人们已经知道,包括某些鞘脂在内的过量脂质积累会对细胞中的胰岛素作用和葡萄糖代谢产生不利影响。在这个项目中,我们将结合多种策略来测试鞘脂谱可以被操纵以对代谢产生有利影响的假设。
英文摘要
Sphingolipids are a class of lipid metabolites that have a variety of functions within cells. It has been known for some time that an accumulation of excess lipid, including certain sphingolipids, can adversely impact insulin action and glucose metabolism in cells. In this project we will a combination of strategies to test the hypothesis that the sphingolipid profile can be manipulated to have favourable effects on metabolism.
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Understanding sphingolipid mediators of insulin resistance
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批准号:nhmrc : 1126135
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项目类别:Project Grants
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资助金额:$43.91万
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财政年份:2017
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负责人:A/Pr Anthony Don
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依托单位:
Restoring neuroprotective sphingosine 1-phosphate signalling in Alzheimer’s Disease
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批准号:nhmrc : 1100626
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项目类别:Project Grants
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资助金额:$59.02万
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财政年份:2016
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负责人:A/Pr Anthony Don
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依托单位:
Restoring neuroprotective sphingosine 1-phosphate signalling in Alzheimer’s Disease
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批准号:nhmrc : GNT1100626
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项目类别:Project Grants
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资助金额:$85.77万
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财政年份:2016
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负责人:A/Pr Anthony Don
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依托单位:
Altered Myelin Sphingolipid Homeostasis in Alzheimer's Disease
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批准号:nhmrc : 1024966
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项目类别:Project Grants
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资助金额:$41.98万
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财政年份:2012
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负责人:A/Pr Anthony Don
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依托单位:
Role of phospholipid scramblase in response of cells to growth factors and cytokines
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批准号:nhmrc : 300606
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项目类别:Early Career Fellowships
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资助金额:$22.12万
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财政年份:2004
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负责人:A/Pr Anthony Don
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依托单位:
海外基金