Evolution and development of the visual system in fish

长期以来，视觉生态学领域的研究试图通过比较生活在不同环境中的鱼类，或通过测试不同背景/刺激下的视觉系统效率来了解鱼类视觉的进化。在这里，我们将重点放在通过斑马鱼的基因敲除、敲除、错误表达和转基因改变视网膜特征来测试有关特征适应价值的假设。我们将改变斑马鱼及其近亲的光感受器的灵敏度和模式。基因工程鱼将在视觉系统、生理和行为模式中进行测试，以确定它们的视觉能力。因此，我们将把发育机制/形态的数据与视觉敏感度和敏锐度的记录结合起来。这一总体方法将用于调查：

A long history of research in the field of Visual Ecology has attempted to understand the evolution of fish vision by comparing fish that live in different environments, or by testing visual system efficiencies with varied backgrounds/stimuli. Here we focus instead on testing hypotheses regarding the adaptive value of characters by altering retinal features through gene knockout, knockdown, mis-expression and transgenesis in zebrafish. We will modify the sensitivity and patterns of photoreceptors in zebrafish and their close relatives. The engineered fish will be tested in paradigms of visual system physiology and behaviour to define their visual abilities. Thus we will integrate data of developmental mechanisms/morphology with recordings of visual sensitivity and acuity. This overall approach will be used to investigate: