Advances in optical coherence tomography

光学相干层析成像的研究进展。我们建议继续研究光学相干断层成像技术，在超宽带操作、同步共聚焦门扫描和色散补偿等关键领域取得实质性的新进展。这些进展旨在将分辨率提高到1-5微米范围，这将使亚细胞体内成像取得突破，使原位样品组织学可见，这在目前是不可能的。我们还计划在扫描延迟线技术的关键领域取得进展，首次将声光技术应用于OCT。声光技术具有无运动部件、扫描速度快、精度高等优点。

Advances in optical coherence tomography. We propose to continue our research into the biomedical imaging technique of optical coherence tomography by making substantial new advances in the key areas of ultra-broad bandwidth operation, coincident confocal gate scanning, and dispersion compensation. These advances are aimed at improving resolution to the 1-5 micron range, which should allow a breakthrough to sub-cellular in vivo imaging, making visible sample histology in situ, which is currently not possible. We also plan to make advances in the key area of scanning delay line technology by employing acousto-optics in OCT for the first time. Acousto-optics conveys advantages in no-moving-parts, scan-speed and accuracy.