Peptide synthesizer for research in pharmacology and medicinal chemistry. Synthétiseur de peptides pour la recherche en pharmacologie et chimie médicinale.

肽是氨基酸的小聚合物，对生物体的正常功能至关重要。肽是多种生理功能的信使，如炎症、疼痛、炎症、血压等。因此，肽及其相关靶点的结构/功能研究对于理解与许多疾病相关的各种代谢途径的功能至关重要。我们的研究计划需要一个肽合成系统，用于生产进行这些项目所需的各种肽和类似物。我们研究计划的一个重要方面是开发用于诊断各种癌症的新工具。我们的生物标记物是经过修饰的肽衍生物，可在医学成像中提供更好的对比度。我们研究计划的另一个重要方面是开发肽工具来研究生物相互作用（蛋白质/蛋白质，蛋白质/肽）。所需的肽合成系统也将用于产生肽库：这是我们的结构/功能研究所必需的功能。此外，肽合成仪的收购也将为我们提供并行生产几种肽的可能性;从而提高我们研究单位的生产力。该系统对我们的几项研究具有开创性意义;它将使我们能够在药理学和药物化学方面进行最先进的研究。

Peptides are small polymers of amino acids essential for the correct functioning of living organisms. Peptides are messengers for a variety of physiological functions inflammation, pain, glycemia, blood pressure, etc. Consequently, structure/function studies of peptides and their associated targets are of crucial importance to understand the function of various metabolic pathways associated to many diseases. Our research program requires a peptide synthesizer system for the production of the various peptides and analogues necessary to conduct these projects. An important aspect of our research program targets the development of new tools for the diagnostic of various types of cancer. Our biomarkers are peptide derivatives modified to offer a better contrast in medical imaging. Another important aspect of our research program targets the development of peptidic tools to study biological interactions (protein/protein, protein/peptide). The required peptide synthesizer system will also be used to produce peptide libraries: a feature essential for our structure/function studies. Moreover, the acquisition of the peptide synthesizer will also provide us with the possibility to make in parallel several peptides; thus increasing the productivity of our research unit. This system is seminal for several of our studies; it will allow us to pursue our state of the art research in pharmacology and medicinal chemistry.