Genetic and environmental contributions to diversity in salmon maturation and migratory life histories

鲑鱼通常被认为是本地适应的，因为它们出生时以家为家，生活史也有显著的变化；然而，几乎没有经验证据支持这一点。加性遗传方差是适应的重要组成部分，但环境、表观遗传学、非加性遗传和表型可塑性也在快速进化和局部适应中发挥作用。我建议使用分子、种群和数量遗传方法结合田间测量来量化各种遗传、表观遗传和环境对太平洋鲑鱼成熟和迁徙生活史特征的影响。太平洋鲑鱼是我研究的理想模式生物，因为它们表现出极端的生活史变化，经历了强烈的选择(因为它们在产卵后死亡)；我提议的研究将利用我在鲑鱼遗传学、生态学和生理学方面的经验来评估太平洋鲑鱼的快速进化和局部适应。

Salmon are often thought to be locally adapted due to their natal homing and remarkable life history variation; yet little empirical evidence exists to support this. Additive genetic variance is an important component of adaptation, yet environment, epigenetics, non-additive genetics, and phenotypic plasticity also have roles in rapid evolution and local adaptation. I propose to use molecular, population, and quantitative genetic methods combined with field measurements to quantify the various genetic, epigenetic and environmental effects on maturation and migration life history traits in Pacific salmon. Pacific salmon are ideal model organisms for my research as they exhibit extreme life history variation and experience strong selection (since they die after spawning); my proposed research will capitalize on my experience in salmon genetics, ecology and physiology to assess rapid evolution and local adaptation in Pacific salmon.