ASP & hormone control of fat storage in mice

脂肪组织中的脂肪是能量储存的重要组成部分，实际上是身体可用能量的主要来源。过多或过少的脂肪（动物和人类）会改变正常的生理机能，导致许多生理过程的中断。过多的脂肪组织会改变全身的葡萄糖代谢，而脂肪储存在肝脏、胰腺、肌肉和肾脏等其他组织中，会破坏它们的正常功能，导致免疫调节改变。相反，脂肪过少会导致生育问题、胰岛素作用异常、免疫功能改变、迁徙（鸟类）、产卵（鱼类）和冬眠（哺乳动物）的变化。

Fat, in adipose tissue, is an essential component of energy storage and in fact is the major source of body energy available. Too much or too little fat (in animals and humans) can alter normal physiology resulting in disruptions in many physiological processes. excess fat tissue leads to changed whole-body glucose metabolism while fat depots in other tissues, such as liver, pancreas, muscle and kidneys can disrupt their normal function and cause altered immune regulation. Conversely, too little fat can lead to fertility problems, abnormal insulin action, altered immune function, changes in migration (birds), spawning (fish) and hibernation (mammals).